| Type | Description |
|---|---|
| Definition | granulin precursor |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 10:29:00 | Study demonstrated that the level of PGRN protein in the cerebral cortex was significantly increased after microsphere-induced cerebral embolism (ME). Furthermore, PGRN was expressed in the microglia of the ipsilateral hemisphere after ME. | 31640144 |
| 2019-05-18 11:11:00 | PGRN can reduce neuronal apoptosis by mitigating ER stress in the reactive astrocytes as well as downregulating the inflammatory levels by suppressing the NF-kappaB signaling pathway. | 29665049 |
| 2019-01-05 11:36:00 | PGRN is associated with intervertebral disc degeneration through interfering with IL-10 and IL-17 | 29992506 |
| 2018-07-14 11:23:00 | MiR-29b-3p promotes chondrocyte apoptosis and facilitates the occurrence and development of osteoarthritis by targeting PGRN. | 28609022 |
| 2014-08-09 11:08:00 | Activity-dependent secretion of pro-granulin can regulate synapse number and structure. | 24046442 |
| Type | IDs |
|---|---|
| Synonymous | PEPI, PGRN |
| Gene |
UniProtKB-ID:
GRN_RAT,
F1LMP7_RAT,
Q6IN42_RAT,
G3V8V1_RAT
UniprotKB:
P23785,
F1LMP7,
Q6IN42,
G3V8V1
UniParc:
UPI00003782B8,
UPI000157E8E2,
UPI0001963770,
UPI000012BAF0
EMBL:
CH473948,
X62322,
BC072469,
AC134158,
M97750
Ensembl:
ENSRNOG00000021031
KO:
rno:29143
|
| Nucleutide sequences |
EMBL-CDS:
AAA16903.1,
CAA44198.1,
AAH72469.1,
EDM06207.1
Gene_ORFName:
rCG_33205
Ensembl_TRS:
ENSRNOT00000040472,
ENSRNOT00000028557
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000043881,
ENSRNOP00000028557
RefSeq:
NP_058809.2,
NP_001139314.1,
XP_008766203.1
|
| Others |
UniRef100:
UniRef100_G3V8V1,
UniRef100_P23785,
UniRef100_F1LMP7
UniRef90:
UniRef90_P23785
UniRef50:
UniRef50_P28799
UniGene:
Rn.5820
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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