| Type | Description |
|---|---|
| Definition | glutamate metabotropic receptor 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:29:00 | Infiltrating Myeloid Cells Drive Osteosarcoma Progression via GRM4 Regulation of IL23. | 31527131 |
| 2020-03-07 10:25:00 | This is the evidence supporting the interaction between GRM4 and CBX4, which could inhibit the malignant behavior of osteosarcoma cells through the GRM4/CBX4/HIF-1alpha signaling pathway | 31581881 |
| 2020-02-22 12:49:00 | Ectopic expression of glutamate metabotropic receptors (GRM) is correlated with better prognosis of breast cancer (BC)patients. Overexpression of GRM4 significantly inhibits cell proliferation, migration and invasion capacity in BC cell line MDA-MB-231. Overexpression of miR-328-3p and miR-370-3p counteracts the inhibitory effect of GRM4-induced cell proliferation, migration and invasion. | 31492116 |
| 2020-01-11 10:50:00 | Results supply an important evidence that mGluR4 is expressed in prenatal human cerebrum, and main kinds of cells related to neurogenesis are involved in its expression. | 30954358 |
| 2019-11-16 12:26:00 | We identified multiple novel associations of genetic variants in GRM3, GRM4, and GRM5 with the risk and the survival of renal cell carcinoma (RCC). These relationships were supported by gene expression profiles obtained using bioinformatics analysis. Specifically, the expression of GRM4 and GRM5 showed an increasing trend in RCC tissues, compared to that in normal tissue, whereas GRM3 was downregulated in RCC. | 30488581 |
| Type | IDs |
|---|---|
| Synonymous | GPRC1D, MGLUR4, mGlu4 |
| Gene |
UniProtKB-ID:
GRM4_HUMAN,
A8K0J8_HUMAN,
A1L4F9_HUMAN,
B7ZLU9_HUMAN
UniprotKB:
Q14833,
A8K0J8,
A1L4F9,
B7ZLU9
UniParc:
UPI0001914AEE,
UPI000020DB61,
UPI000035E829,
UPI0002065433,
UPI00005A7B0C,
UPI000189A761,
UPI000004A7DE
EMBL:
X80818,
BC130528,
AL590403,
AK289563,
AK122982,
AK293913,
BC144057,
BC130526,
U92457,
CH471081,
AK131536,
AK122836,
AL354740,
AK293949,
EU432124
Ensembl:
ENSG00000124493
KO:
hsa:2914
|
| Nucleutide sequences |
EMBL-CDS:
BAH11632.1,
BAG53831.1,
CAA56784.1,
AAB51762.1,
BAH11625.1,
BAD18673.1,
BAF82252.1,
BAG53752.1,
ABY87923.1,
AAI30527.1,
EAX03759.1,
AAI30529.1,
AAI44058.1
Gene_ORFName:
hCG_41255
Ensembl_TRS:
ENST00000609222,
ENST00000374177,
ENST00000538487,
ENST00000544773,
ENST00000455714,
ENST00000535756,
ENST00000374181
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363292,
ENSP00000398456,
ENSP00000437925,
ENSP00000440556,
ENSP00000437730,
ENSP00000477466,
ENSP00000363296
RefSeq:
NP_000832.1,
NP_001269776.1,
NP_001243740.1,
NP_001243738.1,
NP_001243741.1,
NP_001243742.1
|
| Others |
UniRef100:
UniRef100_B7ZLU9,
UniRef100_A0A2J8NYS9,
UniRef100_Q14833
UniRef90:
UniRef90_P31423
UniRef50:
UniRef50_P31423
UniGene:
Hs.429018,
Hs.736330
CCDS:
CCDS4787.1,
CCDS59010.1,
CCDS59012.1,
CCDS59011.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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