| Type | Description |
|---|---|
| Definition | ATPase Na+/K+ transporting subunit alpha 4 |
| Date | Results | Publications |
|---|---|---|
| 2017-07-01 10:22:00 | Ouabain interactions with the alpha4 isoform of the sodium pump trigger non-classical steroid hormone signaling and integrin expression in spermatocytes. | 27599714 |
| 2016-07-30 10:05:00 | Atp1a4 is tuned for changing extracellular environments during sperm capacitation. | 26476261 |
| 2013-03-02 11:43:00 | Na,K-ATPase alpha4 activity is up-regulated during sperm capacitation through mechanisms that involve both increases in molecular activity and levels of alpha4 at the sperm plasma membrane. | 22441762 |
| 2011-05-21 10:34:00 | These results provide new genetic evidence for the role of the ATP1A4 isoform in sperm motility, under both noncapacitating and capacitating conditions. | 20826726 |
| 2010-08-02 11:34:00 | In sperm, alpha4 is isoform primarily involved in controlling transmembrane Na+ gradient; alpha4 activity is necessary for maintaining membrane potential, [Ca2+]i, and [H+]i. Thus, alpha4 activity is necessary to maintain sperm motility. | 20179187 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
AT1A4_RAT,
Q5PQV3_RAT
UniprotKB:
Q64541,
Q5PQV3
UniParc:
UPI0000124FC6,
UPI00004966FC
EMBL:
U15176,
BC087015
Ensembl:
ENSRNOG00000032378
KO:
rno:29132
|
| Nucleutide sequences |
EMBL-CDS:
AAB81285.1,
AAH87015.1
Ensembl_TRS:
ENSRNOT00000064601
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000062079
RefSeq:
NP_074039.1,
XP_017454251.1,
NP_001257959.1
|
| Others |
UniRef100:
UniRef100_Q64541
UniRef90:
UniRef90_Q9WV27
UniRef50:
UniRef50_Q9WV27
UniGene:
Rn.224462
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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