| Type | Description |
|---|---|
| Definition | glutamate metabotropic receptor 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-16 12:26:00 | We identified multiple novel associations of genetic variants in GRM3, GRM4, and GRM5 with the risk and the survival of renal cell carcinoma (RCC). These relationships were supported by gene expression profiles obtained using bioinformatics analysis. Specifically, the expression of GRM4 and GRM5 showed an increasing trend in RCC tissues, compared to that in normal tissue, whereas GRM3 was downregulated in RCC. | 30488581 |
| 2019-03-02 10:17:00 | this study demonstrates that metastasized cells are less migratory due in part to the post-metastatic downregulation of S100A4 and GRM3. Targeting S100A4 and GRM3 may help prevent bone metastasis. | 28615627 |
| 2019-02-23 11:17:00 | strong interaction between glutamate and Cl(-) ions allows the mGlu3 receptor to sense and efficiently react to sub-micromolar concentrations of glutamate, making it the most sensitive member of mGluR family | 30102917 |
| 2019-01-19 10:26:00 | Tumor-associated GRM3 variants disrupted trafficking of melanosomes, causing their aggregation in the cell body in a cAMP-dependent manner. | 28646617 |
| 2018-07-14 11:13:00 | experiments indicate that mGlu3Delta4 may negatively modulate mGlu3, and thereby impact on the roles of GRM3/mGlu3 in schizophrenia and as a therapeutic target | 28655286 |
| Type | IDs |
|---|---|
| Synonymous | GLUR3, GPRC1C, MGLUR3, mGlu3 |
| Gene |
UniProtKB-ID:
GRM3_HUMAN,
A4D1D0_HUMAN
UniprotKB:
Q14832,
A4D1D0
UniParc:
UPI0000EE5768,
UPI0000153EFC
EMBL:
X77748,
AC004829,
BC022496,
CH471091,
DQ315361,
CH236949,
BC041407,
AC005009,
AC002081,
EU432123
Ensembl:
ENSG00000198822
KO:
hsa:2913
|
| Nucleutide sequences |
EMBL-CDS:
AAC60379.2,
AAD15616.1,
ABC47402.1,
AAH41407.1,
CAA54796.1,
AAH22496.2,
EAW76972.1,
EAL24182.1,
ABY87922.1
Gene_ORFName:
tcag7.244,
hCG_17203
Ensembl_TRS:
ENST00000439827,
ENST00000361669
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000398767,
ENSP00000355316
RefSeq:
NP_000831.2,
XP_016867562.1,
NP_001350451.1
|
| Others |
UniRef100:
UniRef100_Q14832
UniRef90:
UniRef90_P31422
UniRef50:
UniRef50_P31422
UniGene:
Hs.590575
CCDS:
CCDS5600.1,
CCDS87515.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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