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29121 CLEC2D

29121

CLEC2D

C-type lectin domain family 2 member D

protein-coding

Homo sapiens

基因描述

Type Description
Definition C-type lectin domain family 2 member D

研究结论

Date Results Publications
2020-12-19 13:45:00 Role of LLT1 and PCNA as Natural Killer Cell Immune Evasion Strategies of HCT 116 Cells. 33288556
2020-08-22 15:28:00 Docetaxel suppresses immunotherapy efficacy of natural killer cells toward castration-resistant prostate cancer cells via altering androgen receptor-lectin-like transcript 1 signals. 32449811
2020-02-08 11:37:00 The authors identify Clec2d as a sensor for cell death through histone recognition and show that such interaction in macrophages shuttles histone-DNA complexes into endosomes to stimulate toll-like receptors. The consequent inflammation amplifies collateral tissue damage in a liver injury model. 31859049
2019-12-14 10:20:00 LLT1 strong expression was a significant risk factor for nodal metastasis in patients with head and neck cutaneous squamous cell carcinoma (cSCC) and for cSCC specific mortality. Strong LLT1 expression is an independent predictor of nodal metastasis and poor disease-specific survival and it might be helpful for risk stratification of patients with cSCC. 30955082
2019-09-21 12:09:00 REVIEW: Biological and Clinical Significance of Human NKRP1A/LLT1 Receptor/Ligand Interactions 31002602

名称对应

Type IDs
Synonymous CLAX, LLT1, OCIL
Gene
UniProtKB-ID: CLC2D_HUMAN, W8JXM2_HUMAN
UniprotKB: Q9UHP7, W8JXM2
UniParc: UPI0001D63182, UPI000003779D, UPI0001D63181, UPI000006DF3A, UPI000049DD61, UPI0000E594B1
EMBL: BC019883, AC010186, CH471094, KF971858, AF285088, AY144606, FN813349, AF133299, FN813351, AF285089, AC007068, FN813350, AF285087
Ensembl: ENSG00000069493
KO: hsa:29121
Nucleutide sequences
EMBL-CDS: CBL81071.1, EAW96114.1, AAG00516.1, AAG00514.1, AAF22159.1, AAH19883.1, AAN59996.1, CBL81072.1, CBL81070.1, AAG00515.1, AHK61107.1
Ensembl_TRS: ENST00000261339, ENST00000545918, ENST00000290855, ENST00000543300, ENST00000479877, ENST00000261340
Protein sequencees
Ensembl_PRO: ENSP00000261340, ENSP00000290855, ENSP00000441653, ENSP00000261339, ENSP00000443065, ENSP00000444818
RefSeq: NP_037401.1, NP_001184248.1, NP_001184247.1, NP_001184246.1, NP_001004419.1
Others
UniRef100: UniRef100_Q9UHP7, UniRef100_W8JXM2
UniRef90: UniRef90_Q9UHP7
UniRef50: UniRef50_Q9UHP7
UniGene: Hs.268326
CCDS: CCDS31741.1, CCDS55800.1, CCDS55802.1, CCDS8602.1, CCDS55801.1

全选

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