| Type | Description |
|---|---|
| Definition | glutamate metabotropic receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:34:00 | Conformational rearrangement during activation of a metabotropic glutamate receptor. | 33398167 |
| 2020-08-01 13:00:00 | This study investigates the role of unstructured loop (or "BC loop") in Glutamate induced conformation of mGluR2 and its activation. mGluR2 without BC loop does not respond to Glutamate. | 31706572 |
| 2019-03-30 11:37:00 | data suggests that glutamatergic activity through GRM2 in cerebral cortex may differ with gender and suicide ideation. | 30326345 |
| 2018-11-03 10:53:00 | mGlu2 receptors can play an influential role in reducing the probability of glutamate neurotransmitter release and potentially effect seizure activity. | 29360159 |
| 2018-03-17 12:10:00 | Studies support a role for NHERF-1 and NHERF-2 (Na+/H+ exchanger regulatory factors 1 and 2) in regulating the distribution of Group II metabotropic glutamate receptor (mGluRs) in the murine brain, while conversely the effects of the mGluR2/3 PDZ-binding motifs on receptor signaling are likely mediated by interactions with other PDZ scaffold proteins beyond the NHERF proteins. | 28392297 |
| Type | IDs |
|---|---|
| Synonymous | GLUR2, GPRC1B, MGLUR2, mGlu2 |
| Gene |
UniProtKB-ID:
GRM2_HUMAN
UniprotKB:
Q14416
UniParc:
UPI000013E346
EMBL:
EU432122,
L35318,
BC113615,
BC113619,
AB045011,
AY999299,
CH471055
Ensembl:
ENSG00000164082
KO:
hsa:2912
|
| Nucleutide sequences |
EMBL-CDS:
EAW65150.1,
AAY14640.1,
BAB19817.1,
AAA76855.1,
AAI13616.1,
ABY87921.1,
AAI13620.1
Ensembl_TRS:
ENST00000395052
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000378492
RefSeq:
NP_000830.2,
NP_001336046.1,
XP_011531937.1,
NP_001336045.1,
XP_011531938.1,
XP_024309258.1,
XP_011531944.1,
XP_011531939.1,
XP_016861760.1,
XP_011531945.1
|
| Others |
UniRef100:
UniRef100_Q14416
UniRef90:
UniRef90_Q14416
UniRef50:
UniRef50_Q14416
UniGene:
Hs.121510
CCDS:
CCDS2834.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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