| Type | Description |
|---|---|
| Definition | DEAD-box helicase 25 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:03:00 | Characterization of the Phosphorylation Site of GRTH/DDX25 and A Binding Interface Provides Structural Basis for the Design of a Non-Hormonal Male Contraceptive. | 31040297 |
| 2015-06-27 10:11:00 | Analysed the association of GRTH gene IVS6+55G/T and c.852C/T polymorphisms with male infertility. The c.852 T allele was associated with an increased risk of male infertility (OR: 3.16, P = 0.008), whereas IVS6+55G/T allele conferred no risk. | 24168058 |
| 2010-06-30 22:05:00 | Observational study of gene-disease association. (HuGE Navigator) | 20378615 |
| 2010-06-28 11:08:00 | multifunctional RNA helicase that is an essential regulator of spermatogenesis | 19875492 |
| 2010-01-21 00:00:00 | The association of GRTH mutations with male infertility underlines the importance of GRTH as a central, post-transcriptional regulator of spermatogenesis. | 17889551 |
| Type | IDs |
|---|---|
| Synonymous | GRTH |
| Gene |
UniProtKB-ID:
DDX25_HUMAN,
A0A384NYS3_HUMAN
UniprotKB:
Q9UHL0,
A0A384NYS3
UniParc:
UPI000013D425,
UPI000018CE78
EMBL:
AY735309,
AY735310,
AF155140,
AY735312,
AY735302,
AY735305,
AY735303,
AY735308,
AK312772,
BC050360,
CH471065,
AY735301,
AY735306,
GQ900950,
AY735307,
AY735304,
AY735311,
BC035388
Ensembl:
ENSG00000109832
KO:
hsa:29118
|
| Nucleutide sequences |
EMBL-CDS:
AAF21371.2,
EAW67669.1,
AAH35388.2,
AAH50360.2,
AAU84667.1,
BAG35637.1,
ADO22467.1
Ensembl_TRS:
ENST00000525943,
ENST00000263576
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000490224,
ENSP00000263576
RefSeq:
NP_037396.3,
NP_001317367.1,
XP_011541093.1,
XP_011541092.1
|
| Others |
UniRef100:
UniRef100_A0A384NYS3,
UniRef100_Q9UHL0
UniRef90:
UniRef90_F7AQN6,
UniRef90_Q9UHL0
UniRef50:
UniRef50_Q9UMR2,
UniRef50_F7AQN6
UniGene:
Hs.420263
CCDS:
CCDS81646.1,
CCDS44766.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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