| Type | Description |
|---|---|
| Definition | myosin regulatory light chain interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:46:00 | IDOL gene variant is associated with hyperlipidemia in Han population in Xinjiang, China. | 32868861 |
| 2021-02-06 13:58:00 | Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site. | 32727844 |
| 2020-04-18 11:21:00 | IDOL(G51S) is a gain-of-function variant responsible for high LDL-C in both humans and mice. These results suggest that IDOL is a key player regulating cholesterol level in humans. | 31597442 |
| 2016-12-31 11:15:00 | the effects caused by human inducible degrader of the low-density lipoprotein expression are LDLR- dependent given the unchanged plasma lipids in LAhB mice lacking low-density lipoprotein receptor | 26786161 |
| 2016-12-16 14:47:00 | The long noncoding RNA RP1-13D10.2 may contribute to LDL cholesterol levels in response to statins. | 27071970 |
| Type | IDs |
|---|---|
| Synonymous | IDOL, MIR |
| Gene |
UniProtKB-ID:
MYLIP_HUMAN,
Q5TIA5_HUMAN
UniprotKB:
Q8WY64,
Q5TIA5
UniParc:
UPI000006CDE0,
UPI0000E5ACB8,
UPI000045367D
EMBL:
AF187016,
AF006003,
AF212221,
CH471087,
AF258586,
AL021407,
BC002860,
AF006004,
BT007055
Ensembl:
ENSG00000007944
KO:
hsa:29116
|
| Nucleutide sequences |
EMBL-CDS:
AAQ13408.1,
AAP35704.1,
AAF87323.1,
AAH02860.1,
EAW55366.1,
AAQ13409.1,
AAG23789.1,
AAF18974.1,
EAW55367.1
Gene_ORFName:
PP5242,
BM-023,
hCG_37431
Ensembl_TRS:
ENST00000356840,
ENST00000349606
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000349298,
ENSP00000008686
RefSeq:
NP_037394.2,
XP_005249089.1,
XP_005249090.1,
XP_016866278.1
|
| Others |
UniRef100:
UniRef100_Q8WY64
UniRef90:
UniRef90_Q8WY64
UniRef50:
UniRef50_Q8WY64
UniGene:
Hs.484738
CCDS:
CCDS4536.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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