| Type | Description |
|---|---|
| Definition | N-6 adenine-specific DNA methyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:47:00 | Structural insight into HEMK2-TRMT112-mediated glutamine methylation. | 32969463 |
| 2020-07-11 12:39:00 | The down-regulation of TRMT112 does not affect the N6AMT1 protein levels in cells, suggesting that the two proteins of TRMT112 network, WBSCR22 and N6AMT1, are differently regulated by their common cofactor. | 31466382 |
| 2019-12-14 12:26:00 | data link H4K12 methylation with KMT9-dependent regulation of androgen-independent prostate tumor cell proliferation, thereby providing a promising paradigm for the treatment of castration-resistant prostate cancer | 31061526 |
| 2019-03-30 11:08:00 | The abundance of 6mA was significantly lower in cancers, accompanied by decreased N6AMT1 and increased ALKBH1 levels, and downregulation of 6mA modification levels promoted tumorigenesis. Collectively, Results demonstrate that DNA 6mA modification is extensively present in human cells and the decrease of genomic DNA 6mA promotes human tumorigenesis. | 30017583 |
| 2018-04-07 10:22:00 | combined effect of N6AMT1 haplotype 2_GGCCAT and As3MT haplotype 2_GCAC showed consistence with the additive significance of each haplotype on % iAs: the mean was 5.47% and 9.36% for carriers with both and null haplotypes, respectively | 27637898 |
| Type | IDs |
|---|---|
| Synonymous | C21orf127, HEMK2, MTQ2, N6AMT, PRED28, m.HsaHemK2P |
| Gene |
UniProtKB-ID:
N6MT1_HUMAN
UniprotKB:
Q9Y5N5
UniParc:
UPI000003B020,
UPI000006F6F1
EMBL:
KC877845,
KF570251,
AL163248,
AMYH02037685,
CH471079,
AF227510,
KF457188,
BC011554,
AK314100,
AF139682
Ensembl:
ENSG00000156239
KO:
hsa:29104
|
| Nucleutide sequences |
EMBL-CDS:
EAX09939.1,
AAD38520.1,
EAX09940.1,
CAB90428.1,
EAX09941.1,
AAH11554.1,
BAG36794.1
Ensembl_TRS:
ENST00000460212,
ENST00000351429,
ENST00000303775
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000436490,
ENSP00000303584,
ENSP00000286764
RefSeq:
NP_037372.4,
NP_877426.4
|
| Others |
UniRef100:
UniRef100_Q9Y5N5
UniRef90:
UniRef90_Q9Y5N5
UniRef50:
UniRef50_Q9Y5N5
UniGene:
Hs.163846
CCDS:
CCDS33525.1,
CCDS33526.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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