| Type | Description |
|---|---|
| Definition | RAN guanine nucleotide release factor |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 11:07:00 | The MOG1 domain required for the interaction with Nav1.5 to the region spanning amino acids 146-174, and a refined deletion analysis further narrowed this domain to amino acids146-155. | 30282806 |
| 2016-04-23 12:06:00 | Suggest that p.E61X_RANGRF is a rare genetic variation with an uncertain role in Brugada Syndrome. | 24142675 |
| 2015-09-26 16:56:00 | Compound mutation of CACNA2D1 and RANGRF genes were found. To the best of our knowledge, this is the first comprehensive description of the concurrence of these two mutations and histiocytoid cardiomyopathy. | 24438356 |
| 2011-10-01 12:07:00 | Results suggest that dominant-negative mutations in MOG1 can impair the trafficking of Na(v)1.5 to the membrane, leading to I(Na) reduction and clinical manifestation of Brugada syndrome. | 21447824 |
| 2011-09-24 12:07:00 | Our screening of Nav1.5 cofactor MOG1 uncovered a novel nonsense variant that appeared to be present at a higher frequency among these patients with atrial fibrillation and Brugada syndrome than control subjects. | 21621375 |
| Type | IDs |
|---|---|
| Synonymous | HSPC165, HSPC236, MOG1, RANGNRF |
| Gene |
UniProtKB-ID:
MOG1_HUMAN
UniprotKB:
Q9HD47
UniParc:
UPI0000073815,
UPI0000072ED6,
UPI0000071300,
UPI000041A0F9
EMBL:
AF168714,
BC100017,
AK290399,
CH471108,
BC012552,
AF265206,
CR457206,
AF265205,
AF161514,
BC006486,
CR749387,
AF151070
Ensembl:
ENSG00000108961
KO:
hsa:29098
|
| Nucleutide sequences |
EMBL-CDS:
CAG33487.1,
EAW90066.1,
AAG01291.1,
EAW90064.1,
AAF87316.1,
BAF83088.1,
AAF36156.1,
EAW90065.1,
AAG01292.1,
AAF29129.1,
CAH18237.1,
AAH12552.1,
AAH06486.1,
AAI00018.1
Gene_ORFName:
HSPC236,
HSPC165,
MDS5
Ensembl_TRS:
ENST00000439238,
ENST00000226105,
ENST00000580434,
ENST00000407006
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000413190,
ENSP00000383940,
ENSP00000462310,
ENSP00000226105
RefSeq:
NP_001171272.1,
NP_001171273.1,
NP_001317056.1,
NP_057576.2
|
| Others |
UniRef100:
UniRef100_Q9HD47
UniRef90:
UniRef90_Q9HD47
UniRef50:
UniRef50_Q9HD47
UniGene:
Hs.408233
CCDS:
CCDS82066.1,
CCDS54086.1,
CCDS54087.1,
CCDS11137.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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