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2909 ARHGAP35

2909

ARHGAP35

Rho GTPase activating protein 35

protein-coding

Homo sapiens

基因描述

Type Description
Definition Rho GTPase activating protein 35

研究结论

Date Results Publications
2020-12-05 13:00:00 p190A RhoGAP induces CDH1 expression and cooperates with E-cadherin to activate LATS kinases and suppress tumor cell growth. 32641858
2020-02-15 13:23:00 Tau regulates the microtubule-dependent migration of glioblastoma cells via the Rho-ROCK signaling pathway. 30659115
2020-02-01 11:27:00 TRIM65 mediates ubiquitination of ARHGAP35, whose degradation leads to elevated Rho GTPase activity and colorectal cancer metastasis. 31332286
2019-09-21 12:13:00 The data reveal a novel mechanism consistent with a tumor-suppressor function for ARHGAP35. 29934311
2019-09-07 11:35:00 results indicate that inactivating mutation of ARHGAP35 in the repeat is rare in colorectal cancer (CRC) with MSI and suggest that ARHGAP35 inactivating mutation may not play an important role in CRC development 28176259

名称对应

Type IDs
Synonymous GRF-1, GRLF1, P190-A, P190A, p190ARhoGAP, p190RhoGAP
Gene
UniProtKB-ID: RHG35_HUMAN
UniprotKB: Q9NRY4
UniParc: UPI0000163F71
EMBL: M73077, BC150257, AF159851, CH471126, AB051509
Ensembl: ENSG00000160007
KO: hsa:2909
Nucleutide sequences
EMBL-CDS: EAW57450.1, AAA58618.1, BAB21813.2, AAF80386.1, AAI50258.1
Ensembl_TRS: ENST00000404338, ENST00000614079, ENST00000672722
Protein sequencees
Ensembl_PRO: ENSP00000483730, ENSP00000500409, ENSP00000385720
RefSeq: XP_024307241.1, NP_004482.4
Others
UniRef100: UniRef100_Q9NRY4
UniRef90: UniRef90_Q9NRY4
UniRef50: UniRef50_Q91YM2
UniGene: Hs.509447
CCDS: CCDS46127.1

全选

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