| Type | Description |
|---|---|
| Definition | BRISC and BRCA1 A complex member 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-04 10:04:00 | Mutation of the RXXPEG motif in the MERIT40 (R28A) disrupted its interaction with TNKS1 and R28A mutant cells displayed multiple mitotic defects including aberrant spindle assembly and chromosome misalignment. | 30571846 |
| 2016-12-31 11:51:00 | Genetic variants in NBA1 may be an important genetic determinant of triple-negative breast cancer susceptibility. | 26848770 |
| 2014-06-28 13:45:00 | MERIT40 interacts with ABRAXAS which is adaptor molecule of BRCA1-complex. | 24667604 |
| 2011-11-26 11:26:00 | findings suggest that germline deleterious mutations in C19orf62 should be rare or absent in familial and nonfamilial breast cancer women | 21431873 |
| 2011-06-04 11:27:00 | NBA1/MERIT40 and BRE interaction is required for the integrity of two distinct deubiquitinating enzyme BRCC36-containing complexes | 21282113 |
| Type | IDs |
|---|---|
| Synonymous | C19orf62, HSPC142, MERIT40, NBA1 |
| Gene |
UniProtKB-ID:
BABA1_HUMAN,
A0A024R7L2_HUMAN,
J3KQS6_HUMAN
UniprotKB:
Q9NWV8,
A0A024R7L2,
J3KQS6
UniParc:
UPI00017A7B77,
UPI0000034E01,
UPI00002036A9,
UPI0002A476F3
EMBL:
AK000578,
AF161491,
AK299493,
CR533526,
AC010463,
AC104522,
AL136692,
BC000788,
CH471106,
AK301193,
BC091491,
BC006244
Ensembl:
ENSG00000105393
KO:
hsa:29086
|
| Nucleutide sequences |
EMBL-CDS:
BAA91268.1,
AAH06244.1,
BAG62773.1,
AAF29106.1,
CAB66627.1,
CAG38557.1,
BAG61451.1,
AAH91491.1,
AAH00788.1,
EAW84584.1,
EAW84585.1
Gene_ORFName:
HSPC142,
hCG_37651
Ensembl_TRS:
ENST00000598188,
ENST00000601043,
ENST00000359435,
ENST00000595632,
ENST00000447614
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000352408,
ENSP00000470920,
ENSP00000471605,
ENSP00000468834,
ENSP00000407826
RefSeq:
NP_054892.2,
NP_001275685.1,
NP_001028721.1,
NP_001275686.1
|
| Others |
UniRef100:
UniRef100_J3KQS6,
UniRef100_Q9NWV8
UniRef90:
UniRef90_Q9NWV8,
UniRef90_J3KQS6
UniRef50:
UniRef50_Q9NWV8,
UniRef50_J3KQS6
UniGene:
Hs.190722
CCDS:
CCDS46012.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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