| Type | Description |
|---|---|
| Definition | C1GALT1 specific chaperone 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:42:00 | Overexpression of Cosmc suppresses cell migration and invasion in different subtypes of breast cancer cells via Tn and T glycans. | 32452513 |
| 2021-03-20 13:22:00 | Cosmc overexpression enhances malignancies in human colon cancer. | 31633299 |
| 2021-02-13 13:29:00 | MicroRNA196b targets COSMC in pediatric IgA nephropathy. | 32186752 |
| 2018-11-03 10:19:00 | In addition, we found that Tn-expressing colorectal cancers (CRC) cell lines had either loss-of-function mutations in Cosmc or reversible Tn antigen expression, which was not caused by the deficiency of T-synthase activity | 30115016 |
| 2018-04-07 11:13:00 | elevated Tn levels in cancer and inflammation may be commonly regulated by the cytokine (TNFa and IL6)-Cosmc signaling axis | 27542280 |
| Type | IDs |
|---|---|
| Synonymous | C1GALT2, C38H2-L1, COSMC, HSPC067, MST143, TNPS |
| Gene |
UniProtKB-ID:
C1GLC_HUMAN
UniprotKB:
Q96EU7
UniParc:
UPI000004C659
EMBL:
AY159319,
AB084170,
AK290111,
AF161552,
AF177284,
BC050441,
AY358642,
BC011930,
AJ238398,
AC011890,
CH471107
Ensembl:
ENSG00000288368,
ENSG00000171155
KO:
hsa:29071
|
| Nucleutide sequences |
EMBL-CDS:
AAH11930.1,
AAN78129.1,
AAQ13670.1,
EAX11873.1,
CAC80277.1,
BAC41493.1,
BAF82800.1,
AAH50441.1,
AAF29039.1,
AAQ89005.1
Gene_ORFName:
UNQ273/PRO310,
HSPC067,
MSTP143
Ensembl_TRS:
ENST00000673568,
ENST00000371313,
ENST00000304661,
ENST00000673177
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000500561,
ENSP00000304364,
ENSP00000360363,
ENSP00000500356
RefSeq:
NP_689905.1,
NP_001011551.1
|
| Others |
UniRef100:
UniRef100_Q96EU7
UniRef90:
UniRef90_Q96EU7
UniRef50:
UniRef50_Q96EU7
UniGene:
Hs.643920
CCDS:
CCDS14602.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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