| Type | Description |
|---|---|
| Definition | glutamate ionotropic receptor NMDA type subunit 2D |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:28:00 | GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons. | 32497062 |
| 2019-11-16 13:08:00 | we identified three patients with novel GRIN2D variants, providing the solid evidence that GRIN2D variants cause epileptic encephalopathy. | 30280376 |
| 2018-12-22 10:21:00 | ultra-rare variants with loss of function (frameshift, nonsense or splice site) in NMDARs genes like GRIN2C and GRIN2D may contribute to possible risk of schizophrenia | 29317596 |
| 2018-07-21 10:42:00 | This study found that NMDAR activation, NR2D in particular, is involved in human fetal lung fibroblast proliferation and collagen production through a potential ERK1/2-mediated mechanism. | 28987794 |
| 2018-01-27 11:08:00 | High GRIN2D expression is associated with colorectal cancer. | 26943033 |
| Type | IDs |
|---|---|
| Synonymous | EB11, EIEE46, GluN2D, NMDAR2D, NR2D |
| Gene |
UniProtKB-ID:
NMDE4_HUMAN,
Q59G17_HUMAN
UniprotKB:
O15399,
Q59G17
UniParc:
UPI00004F6C41,
UPI000013D3DA
EMBL:
AC011527,
AB209292,
U77783,
AC008403
Ensembl:
ENSG00000105464
KO:
hsa:2906
|
| Nucleutide sequences |
EMBL-CDS:
AAC15910.1,
BAD92529.1
Ensembl_TRS:
ENST00000263269
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263269
RefSeq:
XP_011525174.1,
NP_000827.2
|
| Others |
UniRef100:
UniRef100_O15399,
UniRef100_Q59G17
UniRef90:
UniRef90_A0A485P6A8,
UniRef90_O15399
UniRef50:
UniRef50_A0A485P6A8,
UniRef50_Q62645
UniGene:
Hs.445015
CCDS:
CCDS12719.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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