| Type | Description |
|---|---|
| Definition | adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-23 13:11:00 | APPL1 may be a key regulator of insulin resistance in skeletal muscle, and Resistance training may be an important physiological treatment increasing APPL1 expression, which is attenuated in T2 Diabetes. | 29406784 |
| 2017-08-05 10:07:00 | APPL1 gates PI3K activation at the plasma membrane upon long-term potentiation induction. | 27257087 |
| 2015-04-18 12:11:00 | AdipoR1 and the adaptor protein APPL1 mediated the protective effects of gAcrp. In addition, the function of adiponectin and phosphorylation of AMPK were prominently diminished by inhibition of PI3K. | 25099270 |
| 2014-11-22 13:38:00 | Adiponectin increased colocalization of actin and APPL1. | 25108566 |
| 2014-10-04 12:46:00 | a role of adiponectin-stimulated APPL1-AMPK signaling in cell migration in cardiac fibroblasts | 24255018 |
| Type | IDs |
|---|---|
| Synonymous | RGD1309388 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
XP_008769245.1,
XP_017460509.1
|
| Others |
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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||||
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