| Type | Description |
|---|---|
| Definition | mono-ADP ribosylhydrolase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:36:00 | Molecular basis for the MacroD1-mediated hydrolysis of ADP-ribosylation. | 32683309 |
| 2020-12-05 12:59:00 | Comparative analysis of MACROD1, MACROD2 and TARG1 expression, localisation and interactome. | 32427867 |
| 2019-10-19 12:34:00 | We demonstrated that LRP16 positively regulates the Wnt signaling pathway in hepatocellular carcinoma (HCC), which elucidates an important mechanism of HCC cell growth, metastasis, and prognosis. | 29748698 |
| 2019-02-02 10:53:00 | These findings revealed the functions of LRP16 in promoting the inflammatory response through activating the Rac1-MAPK1/ERK pathway in human adipocytes. | 30562745 |
| 2018-05-05 10:34:00 | Here, the authors report that LRP16 selectively interacts and activates double-stranded RNA-dependent kinase (PKR), and also acts as scaffolds to assist the formation of a ternary complex of PKR and IKKbeta, prolonging the polymers of ADP-ribose (PAR)-dependent nuclear factor kappa B (NF-kappaB) transactivation caused by DNA-damaging agents and confers acquired chemoresistance. | 28820388 |
| Type | IDs |
|---|---|
| Synonymous | LRP16 |
| Gene |
UniProtKB-ID:
MACD1_HUMAN
UniprotKB:
Q9BQ69
UniParc:
UPI000006E931
EMBL:
BC007297,
AF202922,
BC008316,
BC000270,
BC003188
Ensembl:
ENSG00000133315
KO:
hsa:28992
|
| Nucleutide sequences |
EMBL-CDS:
AAH08316.1,
AAF15294.2,
AAH00270.2,
AAH07297.1,
AAH03188.1
Ensembl_TRS:
ENST00000255681
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000255681
RefSeq:
XP_011543272.1,
XP_006718585.1,
XP_006718584.1,
XP_005273997.1,
XP_005273996.1,
NP_054786.2
|
| Others |
UniRef100:
UniRef100_Q9BQ69
UniRef90:
UniRef90_Q9BQ69
UniRef50:
UniRef50_Q9BQ69
UniGene:
Hs.602898
CCDS:
CCDS8056.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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