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2899 GRIK3

2899

GRIK3

glutamate ionotropic receptor kainate type subunit 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition glutamate ionotropic receptor kainate type subunit 3

研究结论

Date Results Publications
2019-11-09 10:25:00 Mechanically, GRIK3 influenced a range of signaling pathways and key signal transducers, including two epithelial-mesenchymal transition regulators, SPDEF and CDH1. Moreover, overexpression of GRIK3 increased the expression of mesenchymal markers and decreased the expression of epithelial markers, resulting in the translocation of beta-catenin into the nucleus and the increased beta-catenin transcriptional activity. 30977227
2017-07-22 10:30:00 additional experiment showed that the lymph node metastasis tissues had higher GRIK3 expression than their matched primary gastric cancer (GC) tissues. These findings suggested that elevated GRIK3 expression could serve as an independent prognostic biomarker and a novel potential treatment target for patients with GC. 28631555
2017-03-22 10:11:00 GRIK3 expression is significantly downregulated in human masticatory mucosa during wound healing 28005267
2014-09-13 12:35:00 1p34.3 deletion involving GRIK3: Further clinical implication of GRIK family glutamate receptors in the pathogenesis of developmental delay. 24449200
2013-06-22 11:20:00 Analyses revealed that polymorphism Ser310Ala of GRIK3 gene is not associated with alcohol dependence or any of its subgroups. 23006490

名称对应

Type IDs
Synonymous EAA5, GLR7, GLUR7, GluK3, GluR7a
Gene
UniProtKB-ID: GRIK3_HUMAN
UniprotKB: Q13003
UniParc: UPI000006D54D, UPI000013E311
EMBL: AC117945, AJ249210, U16127, CH471059, AL355386, AL591883, S69349, U16128
Ensembl: ENSG00000163873
KO: hsa:2899
Nucleutide sequences
EMBL-CDS: EAX07351.1, EAX07350.1, AAC50421.1, AAB60407.1, CAC80548.1, AAB30157.1
Ensembl_TRS: ENST00000373091, ENST00000373093
Protein sequencees
Ensembl_PRO: ENSP00000362185, ENSP00000362183
RefSeq: NP_000822.2
Others
UniRef100: UniRef100_Q13003
UniRef90: UniRef90_P42264
UniRef50: UniRef50_P42260
UniGene: Hs.128848
CCDS: CCDS416.1

全选

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