| Type | Description |
|---|---|
| Definition | N-terminal Xaa-Pro-Lys N-methyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:00:00 | Probing the Plasticity in the of Protein N-terminal Methyltransferase 1 Using Bisubstrate Analogues. | 32605369 |
| 2019-05-18 12:37:00 | The NRMT2 expression activates NRMT1 activity, not through priming, but by increasing its stability and substrate affinity. | 30151928 |
| 2018-11-10 10:31:00 | CENP-A undergoes alpha-amino trimethylation by the enzyme NRMT in vivo. | 28266506 |
| 2017-08-26 11:49:00 | NRMT1 mutants N209I (endometrial cancer) and P211S (lung cancer) alter its catalytic activity and decrease N-terminal trimethylation. | 28556566 |
| 2016-03-05 10:53:00 | These studies position the NRMT1 knockout mouse as a useful new system for studying the effects of genomic instability and defective DNA damage repair on organismal and tissue-specific aging. | 25843235 |
| Type | IDs |
|---|---|
| Synonymous | AD-003, C9orf32, HOMT1A, METTL11A, NRMT, NRMT1, NTM1A |
| Gene |
UniProtKB-ID:
NTM1A_HUMAN,
A0A024R8E4_HUMAN,
S4R338_HUMAN
UniprotKB:
Q9BV86,
A0A024R8E4,
S4R338
UniParc:
UPI0001EEBB4F,
UPI000004A00F,
UPI0000470190
EMBL:
AL590369,
BC033234,
AK298840,
AL391056,
AK292332,
BC001396,
AF110776,
AK290957,
CH471090
Ensembl:
ENSG00000148335
KO:
hsa:28989
|
| Nucleutide sequences |
EMBL-CDS:
AAH33234.1,
BAF85021.1,
BAG60968.1,
AAF14859.1,
BAF83646.1,
AAH01396.1,
EAW87895.1,
EAW87893.1
Gene_ORFName:
AD-003,
hCG_30597
Ensembl_TRS:
ENST00000613644,
ENST00000372483,
ENST00000372486,
ENST00000372481,
ENST00000611055,
ENST00000372480,
ENST00000617943,
ENST00000482347
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361561,
ENSP00000478521,
ENSP00000361564,
ENSP00000361558,
ENSP00000483489,
ENSP00000361559,
ENSP00000473900,
ENSP00000484447
RefSeq:
NP_001273731.1,
NP_001273726.1,
XP_016870131.1,
XP_005251996.1,
NP_001273725.1,
NP_001273729.1,
NP_001273728.1,
NP_054783.2,
NP_001273727.1,
NP_001273730.1,
NP_001273732.1
|
| Others |
UniRef100:
UniRef100_Q9BV86
UniRef90:
UniRef90_Q9BV86
UniRef50:
UniRef50_Q9BV86
UniGene:
Hs.744027
CCDS:
CCDS35160.1,
CCDS69682.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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