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28983 TMPRSS11E

28983

TMPRSS11E

transmembrane serine protease 11E

protein-coding

Homo sapiens

基因描述

Type Description
Definition transmembrane serine protease 11E

研究结论

Date Results Publications
2016-08-20 11:37:00 DESC1 may suppress esophageal squamous cell carcinoma development by sensitizing cells to apoptosis under an apoptotic stimulus through downregulating the EGFR/AKT signaling pathway. 26856390
2014-11-29 10:08:00 study demonstrates that two cellular serine proteases, DESC1 and MSPL, activate influenza viruses and emerging coronaviruses in cell culture and, because of their expression in human lung tissue, might promote viral spread in the infected host 25122802
2010-01-21 00:00:00 The domain of DESC1 exhibits a trypsin-like serine proteinase fold with a thrombin-like S1 pocket, a urokinase-type plasminogen activator-type S2 pocket, to accept small residues, and an open hydrophobic S3/S4 cavity to accept large hydrophobic residues. 17388811

名称对应

Type IDs
Synonymous DESC1, TMPRSS11E2
Gene
UniProtKB-ID: TM11E_HUMAN
UniprotKB: Q9UL52
UniParc: UPI00000389F7
EMBL: BC113414, AC019173, AC140484, BC113412, AF064819, AY359017
Ensembl: ENSG00000087128
KO: hsa:28983
Nucleutide sequences
EMBL-CDS: AAQ89376.1, AAI13415.1, AAF04328.1, AAI13413.1
Gene_ORFName: UNQ742/PRO1461
Ensembl_TRS: ENST00000305363
Protein sequencees
Ensembl_PRO: ENSP00000307519
RefSeq: NP_054777.2, XP_011530198.1
Others
UniRef100: UniRef100_Q9UL52
UniRef90: UniRef90_Q9UL52
UniRef50: UniRef50_Q5S248
UniGene: Hs.201877
CCDS: CCDS33993.1

全选

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研究热度

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