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2898 GRIK2

2898

GRIK2

glutamate ionotropic receptor kainate type subunit 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition glutamate ionotropic receptor kainate type subunit 2

研究结论

Date Results Publications
2020-07-04 10:48:00 This study suggests that the rs2227283 polymorphism of the GRIK2 gene is related to aggressive behaviors in bipolar manic patients and that the A/A genotype and A allele may increase the risk of the aggressive behavior in bipolar manic patients. 31631587
2019-07-13 11:02:00 Both the GRIK2 rs4840200-T and rs3213607-A, and the interactions between rs4840200 and rs9390754 are related to the increased risk of epilepsy risk. 30908586
2019-04-13 12:18:00 These results indicate involvement of GRIK2 in senescence and suggests GRIK2 as a potential target for therapeutic intervention of cancer cells. 30587499
2019-03-02 11:45:00 Study identifies differentially variable CpG sites in GRIK2 gene displaying increased expression in patients with chronic obstructive pulmonary disease. 29527240
2018-08-18 10:12:00 results suggest that SUMOylation is an important regulator of the 14-3-3 and GluK2a protein complex and may contribute to regulate the decay kinetics of kainate receptor-excitatory postsynaptic currents 28837400

名称对应

Type IDs
Synonymous EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
Gene
UniProtKB-ID: GRIK2_HUMAN, A8K0H7_HUMAN, Q8IY40_HUMAN
UniprotKB: Q13002, A8K0H7, Q8IY40
UniParc: UPI000287A2DD, UPI0000EADF33, UPI0000EADF32, UPI000006DFF5, UPI000287A2DE, UPI000012B617, UPI00015DA466, UPI000059D903, UPI00000742D9
EMBL: AK289542, AP002528, BC037954, HM149335, AP002529, HM149337, AL109919, CH471051, U16126, HM149336, AP002530, AJ301609, HM149339, AJ301608, HM149338, AJ301610, AJ252246
Ensembl: ENSG00000164418
KO: hsa:2898
Nucleutide sequences
EMBL-CDS: ADH93570.1, CAC67487.1, EAW48448.1, AAC50420.1, CAC67486.1, CAC67485.1, CAC81020.1, ADH93571.1, ADH93573.1, ADH93572.1, ADH93569.1, BAF82231.1, AAH37954.1
Ensembl_TRS: ENST00000421544, ENST00000369138, ENST00000413795
Protein sequencees
Ensembl_PRO: ENSP00000358134, ENSP00000405596, ENSP00000397026
RefSeq: XP_016866270.1, NP_786944.1, XP_016866271.1, NP_068775.1, XP_024302179.1, XP_011534079.1, XP_005267003.1, NP_001159719.1, XP_024302178.1
Others
UniRef100: UniRef100_Q13002, UniRef100_Q8IY40, UniRef100_A8K0H7
UniRef90: UniRef90_A0A2I3MMF9, UniRef90_P39087-2, UniRef90_P42260
UniRef50: UniRef50_P42260, UniRef50_A0A3Q3IAE8, UniRef50_P39087-2
UniGene: Hs.98262
CCDS: CCDS55045.1, CCDS5048.1, CCDS5049.1

全选

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研究热度

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