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2897 GRIK1

2897

GRIK1

glutamate ionotropic receptor kainate type subunit 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition glutamate ionotropic receptor kainate type subunit 1

研究结论

Date Results Publications
2017-11-11 12:37:00 DRD2 A2/A1, DRD3 Ser9Gly, DbetaH -1021C>T, OPRM1 A118G and GRIK1 rs2832407C>A are not associated with alcoholism alone or in interaction. 27447243
2016-12-24 11:06:00 The findings reported here suggest that, in participants with the GRIK1 rs2832407*CC genotype, topiramate treatment enhances self-efficacy and reduces heavy drinking. 25496338
2016-10-22 11:31:00 Findings indicate that SNPs in the GRIK1 gene is associated with altered cue-induced brain activation that is related to craving for alcohol and relapse risk. 26289945
2016-09-03 12:01:00 Results suggested that the extracellular N-terminal region including the two CUB domains was largely responsible for the distinct regulatory effects of Neto1 and Neto2 on the desensitization properties of GluK1 homomeric receptors 26277340
2016-02-27 11:41:00 In the present study, we have shown that gene-gene interaction of components of different systems associated with nicotine reinforcing effects, such as OPRM1 and GRIK1, rather than one gene polymorphism, is associated with smoking behavior. 25941919

名称对应

Type IDs
Synonymous EAA3, EEA3, GLR5, GLUR5, GluK1, gluR-5
Gene
UniProtKB-ID: GRIK1_HUMAN, B7Z256_HUMAN, B7Z3V7_HUMAN, E7EPZ0_HUMAN, E9PD61_HUMAN, E7EPY9_HUMAN, E7ENK3_HUMAN
UniprotKB: P39086, B7Z256, B7Z3V7, E7EPZ0, E9PD61, E7EPY9, E7ENK3
UniParc: UPI0001914B81, UPI0000E5A39A, UPI000012B612, UPI0000E5A39C, UPI0001914B44, UPI0000E5A39B, UPI0000E2583B, UPI000000107B
EMBL: KF511373, KF457193, AK296404, AP000239, KF511371, KF511372, AK294353, L19058, U16125, AP000238, AJ249208, AP000237
Ensembl: ENSG00000171189
KO: hsa:2897
Nucleutide sequences
EMBL-CDS: AAA52568.1, AAA95961.1, CAC80546.1, BAH11742.1, BAH12343.1
Ensembl_TRS: ENST00000399907, ENST00000389125, ENST00000399909, ENST00000399913, ENST00000399914, ENST00000327783
Protein sequencees
Ensembl_PRO: ENSP00000373777, ENSP00000382791, ENSP00000382793, ENSP00000382797, ENSP00000382798, ENSP00000327687
RefSeq: NP_001307547.1, NP_001307559.1, XP_005261001.1, NP_000821.1, NP_783300.1, NP_001307545.1, NP_001307550.1, NP_001317923.1, NP_001317922.1
Others
UniRef100: UniRef100_E7EPZ0, UniRef100_B7Z256, UniRef100_E7EPY9, UniRef100_E9PD61, UniRef100_E7ENK3, UniRef100_B7Z3V7, UniRef100_P39086
UniRef90: UniRef90_A0A1D5PHS4, UniRef90_P22756, UniRef90_P39086, UniRef90_A0A4W2IGI1, UniRef90_M3WA29
UniRef50: UniRef50_Q91755, UniRef50_P39087-2
UniGene: Hs.664641
CCDS: CCDS42913.1, CCDS33530.1

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