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28969 BZW2

28969

BZW2

basic leucine zipper and W2 domains 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition basic leucine zipper and W2 domains 2

研究结论

Date Results Publications
2021-03-13 13:14:00 BZW2 promotes the malignant progression of colorectal cancer via activating the ERK/MAPK pathway. 31643092
2020-08-01 10:16:00 BZW2 has an oncogenic role in muscle-invasive bladder cancer and serves as a promising target for molecular diagnosis and gene therapy. 30932331
2019-12-14 10:48:00 5MP1 is a novel oncogene that reprograms c-Myc translation in CRC. 5MP1 could be a potential therapeutic target to overcome therapeutic resistance conferred by tumor heterogeneity of CRC. 31175057
2018-05-12 10:46:00 These data demonstrated that the knockdown of BZW2 suppresses protein phosphorylation in the Akt/mTOR signaling pathway. These observations suggest that BZW2 is upregulated and has a pro-tumor effect in osteosarcoma via activation of the Akt/mTOR signaling pathway and thus is a potential target for gene therapy. 28791373
2018-04-07 10:55:00 results reveal a surprising role for BZW1 and BZW2 in maintaining homeostatic stringency of start codon selection, and taking into account recent biochemical, genetic and structural insights into eukaryotic initiation, suggest a model for BZW1 and BZW2 function 29470543

名称对应

Type IDs
Synonymous HSPC028, MST017, MSTP017
Gene
UniProtKB-ID: BZW2_HUMAN, A0A024RA42_HUMAN
UniprotKB: Q9Y6E2, A0A024RA42
UniParc: UPI00000700A0, UPI000003B445
EMBL: AK001218, BC107757, BC009597, AF110323, BC003056, AK027837, CH471073, AF083246, CH236948, BC008453
Ensembl: ENSG00000136261
KO: hsa:28969
Nucleutide sequences
EMBL-CDS: AAG39278.1, EAW93678.1, AAH08453.1, BAB55401.1, AAI07758.1, AAD39844.1, AAH03056.1, AAH09597.1, EAW93675.1, BAA91562.1, EAL24285.1, EAW93679.1, EAW93676.1
Gene_ORFName: MSTP017, HSPC028, hCG_19293
Ensembl_TRS: ENST00000258761, ENST00000433922
Protein sequencees
Ensembl_PRO: ENSP00000258761, ENSP00000397249
RefSeq: NP_001349647.1, NP_001349646.1, NP_001153239.1, NP_054757.1, XP_006715770.1, XP_006715771.1, NP_001349648.1
Others
UniRef100: UniRef100_Q9Y6E2
UniRef90: UniRef90_Q9Y6E2
UniRef50: UniRef50_Q9Y6E2
UniGene: Hs.487635
CCDS: CCDS5362.1

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