| Type | Description |
|---|---|
| Definition | osteoclastogenesis associated transmembrane protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:45:00 | Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1. | 32749217 |
| 2020-10-24 14:08:00 | Osteopetrosis-Associated 1 Recruits RNA Exosome To Restrict Hepatitis B Virus Replication. | 32188736 |
| 2019-10-26 11:04:00 | These studies defined bifunctional roles for Ostm1 as a major regulator of preosteoclast cytoskeletal rearrangements toward cell multinucleation and of mature osteoclast intracellular lysosomal trafficking and exocytosis mechanism, both of which are essential for bone resorption. | 29297601 |
| 2017-12-09 13:34:00 | Homozygous splice defect in OSTM1, coexisting with MANEAL mutation was identified in a patient with neurological disorder with brain iron accumulation. | 28612835 |
| 2016-06-11 11:32:00 | KIF5B is essential for Ostm1 intracellular dispersion. | 26598607 |
| Type | IDs |
|---|---|
| Synonymous | GIPN, GL, HSPC019, OPTB5 |
| Gene |
UniProtKB-ID:
OSTM1_HUMAN
UniprotKB:
Q86WC4
UniParc:
UPI00000472C4
EMBL:
BC068581,
Z98200,
CH471051,
AK075012,
AF077205,
BK000461,
AF533891,
AY358795
Ensembl:
ENSG00000081087
KO:
hsa:28962
|
| Nucleutide sequences |
EMBL-CDS:
DAA00039.1,
AAD27000.1,
BAC11351.1,
AAH68581.1,
AAQ89155.1,
EAW48389.1,
AAO72749.1,
EAW48390.1
Gene_ORFName:
UNQ6098/PRO21201,
HSPC019
Ensembl_TRS:
ENST00000193322
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000193322
RefSeq:
NP_054747.2
|
| Others |
UniRef100:
UniRef100_Q86WC4
UniRef90:
UniRef90_Q86WC4
UniRef50:
UniRef50_Q8BGT0
UniGene:
Hs.226780,
Hs.706947,
Hs.745455
CCDS:
CCDS5062.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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