| Type | Description |
|---|---|
| Definition | cytochrome c oxidase assembly factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2017-05-27 10:18:00 | Data suggest that COX assembly factor 3 (hCOA3) is a disordered protein and that the flexibility of hCOA3 is crucial for its interaction with other proteins to favor mitochondrial protein translocation and assembly of proteins involved in the respiratory chain. | 27791355 |
| 2016-03-05 11:51:00 | COX14 was undetectable in COA3 subject fibroblasts, and that COA3 was undetectable in fibroblasts from a COX14 subject, demonstrating the interdependence of these two COX assembly factors | 25604084 |
| 2016-01-30 12:05:00 | Data show that mitochondrial protein ccdc56/MITRAC12/COA3 positively regulates mitochondrial fission by recruiting the fission factor Drp1. | 26358295 |
| 2013-05-18 12:03:00 | hCOA3 stabilizes COX1 co-translationally and promotes its assembly with COX partner subunits. | 23362268 |
| 2013-03-02 10:52:00 | Study comprehensively identified mammalian cytochrome c oxidase assembly factors. These analyses led to the discoveryof MITRAC12, which defines the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase)complexes. | 23260140 |
| Type | IDs |
|---|---|
| Synonymous | CCDC56, COX25, HSPC009, MITRAC12 |
| Gene |
UniProtKB-ID:
COA3_HUMAN,
A0A024R1X4_HUMAN
UniprotKB:
Q9Y2R0,
A0A024R1X4
UniParc:
UPI000006DCB8
EMBL:
BC002698,
CH471152,
AK290863,
AF070665,
AC016889
Ensembl:
ENSG00000183978
KO:
hsa:28958
|
| Nucleutide sequences |
EMBL-CDS:
AAD20971.1,
AAH02698.1,
EAW60884.1,
BAF83552.1,
EAW60885.1
Gene_ORFName:
HSPC009,
hCG_16955
Ensembl_TRS:
ENST00000328434
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354762
RefSeq:
NP_001035521.1
|
| Others |
UniRef100:
UniRef100_Q9Y2R0
UniRef90:
UniRef90_Q9Y2R0
UniRef50:
UniRef50_Q9Y2R0
UniGene:
Hs.16059
CCDS:
CCDS32660.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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