| Type | Description |
|---|---|
| Definition | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-27 10:29:00 | In the two wild type (WT) cases, two novel alterations were detected: a complex deletion of APC and a pathogenic mutation of LAMTOR2. Focusing on WT DT subtype, deep sequencing of CTNNB1, APC and LAMTOR2 was conducted on a retrospective series of 11 WT DT using a targeted approach | 29901254 |
| 2013-07-06 11:24:00 | identified polymorphisms in LAMTOR2 and LAMTOR3 do not seem to play a relevant role in breast cancer | 23341997 |
| 2013-01-26 11:17:00 | The ROBLD3 C-A, thorn23 mutation creates a 50SS capable of recruiting an inhibitory U1 snRNP complex leading to a failure of proper 30 end formation and rapid degradation of p14 mRNA. | 22968171 |
| 2011-12-31 11:26:00 | simulations constitute a multi-dimensional exploration of how EGF-dependent EGFR endocytosis and ERK activation are dynamically affected by scaffolds KSR and MP1, co-regulated by Cbl-CIN85 and Endophilin A1 | 21829671 |
| 2010-07-12 12:17:00 | A complex encoded by the MAPKSP1, ROBLD3, and c11orf59 genes interacts with the Rag GTPases, recruits them to lysosomes, and is essential for mTORC1 activation | 20381137 |
| Type | IDs |
|---|---|
| Synonymous | ENDAP, HSPC003, MAPBPIP, MAPKSP1AP, ROBLD3, Ragulator2, p14 |
| Gene |
UniProtKB-ID:
LTOR2_HUMAN
UniprotKB:
Q9Y2Q5
UniParc:
UPI000045892F,
UPI0000458930,
UPI000012E762
EMBL:
AL355388,
AF070659,
AK307086,
BC024190
Ensembl:
ENSG00000116586
KO:
hsa:28956
|
| Nucleutide sequences |
EMBL-CDS:
AAH24190.1,
AAD20965.1
Gene_ORFName:
HSPC003
Ensembl_TRS:
ENST00000368302,
ENST00000368304,
ENST00000368305
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357287,
ENSP00000357288,
ENSP00000357285
RefSeq:
NP_054736.1,
NP_001138736.1
|
| Others |
UniRef100:
UniRef100_Q9Y2Q5
UniRef90:
UniRef90_Q9Y2Q5
UniRef50:
UniRef50_Q9Y2Q5
UniGene:
Hs.632483
CCDS:
CCDS1128.1,
CCDS44243.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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