| Type | Description |
|---|---|
| Definition | Dexi homolog |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 11:01:00 | These observations support DEXI as the aetiological gene in the type 1 diabetes-associated 16p13 genomic region, and provide the first indication of a link between this candidate gene and the regulation of local antiviral immune responses in beta cells. | 30478640 |
| 2015-01-17 10:46:00 | Reduced DEXI mRNA level was associated with type 1 diabetes risk alleles of CLEC16A. | 25008175 |
| 2013-06-29 12:40:00 | The data indicates a possible regulatory role for multiple sclerosis-associated non-coding CLEC16A SNPs and a common control mechanism for the expression of CLEC16A, SOCS1 and DEXI. | 23151489 |
| 2012-04-28 10:35:00 | DEXI is an unappreciated autoimmune disease candidate gene, and illustrate the power of the 3C approach in progressing from genome-wide association studies results to candidate causal genes | 21989056 |
| 2012-01-21 11:21:00 | Silencing of DEXI leads to drug resistance in colon cancer. | 21901246 |
| Type | IDs |
|---|---|
| Synonymous | MYLE |
| Gene |
UniProtKB-ID:
DEXI_HUMAN
UniprotKB:
O95424
UniParc:
UPI0000001C63
EMBL:
BC071683,
BC052989,
BC001083,
AF108145,
CH471112,
BC037569,
AK314111
Ensembl:
ENSG00000182108
KO:
hsa:28955
|
| Nucleutide sequences |
EMBL-CDS:
BAG36804.1,
AAH52989.1,
AAH01083.2,
AAH37569.1,
EAW85167.1,
AAC83382.2,
AAH71683.1
Ensembl_TRS:
ENST00000469379,
ENST00000570440,
ENST00000331808
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000482265,
ENSP00000493467,
ENSP00000330509
RefSeq:
NP_054734.2
|
| Others |
UniRef100:
UniRef100_O95424
UniRef90:
UniRef90_O95424
UniRef50:
UniRef50_O95424
UniGene:
Hs.592051,
Hs.659355
CCDS:
CCDS10545.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32814053 |
Cell Rep Christian Haenig , Nir Atias , Alexander K Taylor , Arnon Mazza , Martin H Schaefer , Jenny Russ , Sean-Patrick Riechers , Shushant Jain , Maura Coughlin , Jean-Fred Fontaine , Brian D Freibaum , Lydia Brusendorf , Martina Zenkner , Pablo Porras , Martin Stroedicke , Sigrid Schnoegl , Kristin Arnsburg , Annett Boeddrich , Lucia Pigazzini , Peter Heutink , J Paul Taylor , Janine Kirstein , Miguel A Andrade-Navarro , Roded Sharan , Erich E Wanker |
2020-08-18 | - |
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 30478640 |
Diabetologia Reinaldo S Dos Santos , Laura Marroqui , Teresa Velayos , Ane Olazagoitia-Garmendia , Amaia Jauregi-Miguel , Ainara Castellanos-Rubio , Decio L Eizirik , Luis Castaño , Izortze Santin |
2019-03-01 | - |
| 25008175 |
Fine mapping and functional studies of risk variants for type 1 diabetes at chromosome 16p13.13. Diabetes M Joseph Tomlinson , Achilleas Pitsillides , Rebecca Pickin , Matthew Mika , Keith L Keene , Xuanlin Hou , Josyf Mychaleckyj , Wei-Min Chen , Patrick Concannon , Suna Onengut-Gumuscu |
2014-12-01 |
CLEC16A,
DEXI
|
| 23151489 |
Genes Immun. I S Leikfoss , I-L Mero , M K Dahle , B A Lie , H F Harbo , A Spurkland , T Berge |
2013-01-01 |
CLEC16A,
DEXI,
SOCS1
|
| 21989056 |
Hum. Mol. Genet. Lucy J Davison , Chris Wallace , Jason D Cooper , Nathan F Cope , Nicola K Wilson , Deborah J Smyth , Joanna M M Howson , Nada Saleh , Abdullah Al-Jeffery , Karen L Angus , Helen E Stevens , Sarah Nutland , Simon Duley , Richard M R Coulson , Neil M Walker , Oliver S Burren , Catherine M Rice , Francois Cambien , Tanja Zeller , Thomas Munzel , Karl Lackner , Stefan Blakenberg , Cardiogenics Consortium , Peter Fraser , Berthold Gottgens , John A Todd , Tony Attwood , Stephanie Belz , Peter Braund , François Cambien , Jason Cooper , Abi Crisp-Hihn , Patrick Diemert , Panos Deloukas , Nicola Foad , Jeanette Erdmann , Alison H Goodall , Jay Gracey , Emma Gray , Rhian G Williams , Susanne Heimerl , Christian Hengstenberg , Jennifer Jolley , Unni Krishnan , Heather Lloyd-Jones , Ingrid Lugauer , Per Lundmark , Seraya Maouche , Jasbir S Moore , David Muir , Elizabeth Murray , Chris P Nelson , Jessica Neudert , David Niblett , Karen O'Leary , Willem H Ouwehand , Helen Pollard , Angela Rankin , Catherine M Rice , Hendrik Sager , Nilesh J Samani , Jennifer Sambrook , Gerd Schmitz , Michael Scholz , Laura Schroeder , Heribert Schunkert , Ann-Christine Syvannen , Stefanie Tennstedt , Chris Wallace |
2012-01-15 | - |
| 21901246 |
Int. J. Oncol. Yuichiro Miyaki , Koichi Suzuki , Kei Koizumi , Takaharu Kato , Masaaki Saito , Hidenori Kamiyama , Takafumi Maeda , Kiyoshi Shibata , Norihiko Shiya , Fumio Konishi |
2012-01-01 |
DEXI
|
| 16751776 |
A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature Angélique Girard , Ravi Sachidanandam , Gregory J Hannon , Michelle A Carmell |
2006-07-13 | - |
| 16169070 |
A human protein-protein interaction network: a resource for annotating the proteome. Cell Ulrich Stelzl , Uwe Worm , Maciej Lalowski , Christian Haenig , Felix H Brembeck , Heike Goehler , Martin Stroedicke , Martina Zenkner , Anke Schoenherr , Susanne Koeppen , Jan Timm , Sascha Mintzlaff , Claudia Abraham , Nicole Bock , Silvia Kietzmann , Astrid Goedde , Engin Toksöz , Anja Droege , Sylvia Krobitsch , Bernhard Korn , Walter Birchmeier , Hans Lehrach , Erich E Wanker |
2005-09-23 |
Eif4a2,
Tmsb4x,
Supt5,
Trp53,
Tuba1a,
Ppp2r2d,
Ilf2,
Fam101a,
Tubb2b,
Cggbp1,
Sh3d21,
Rab11b,
Dnaja2,
psmd14,
SRA1,
HDAC5,
PDCD6IP,
TOM1L1,
SH2D3C,
UBA2,
DNM1L,
COX17,
SCAMP2,
RWDD2B,
DPP3,
SNUPN,
TSSC4,
PDCD7,
CDH10,
PQBP1,
ARPC4,
ARPC3,
ACTR1B,
TOB1,
TRIM28,
RASA4,
PDZK1IP1,
SERF2,
RBM5,
TNK2,
TXNDC9,
CDK4,
PSME3,
MPHOSPH6,
NUTF2,
PATJ,
EIF1,
FLOT1,
PLIN3,
RASGRP2,
HNRNPR,
MRPS31,
GLYAT,
CDKN1A,
CDK2AP2,
RAMP3,
CDKN1B,
STUB1,
EFS,
SAP18,
PAK4,
DLEU1,
CDKN2B,
APBB3,
CDKN2C,
TFG,
NPM3,
HMG20B,
TUBB3,
TUBB4B,
CORO2B,
NDRG1,
MYL9,
RACK1,
NDC80,
WFDC2,
PRMT5,
ARIH2,
EMG1,
TIMM17A,
PPIE,
HAX1,
BAIAP2,
TADA3,
ATP5H,
EIF3M,
CEACAM5,
LRRC41,
VTI1B,
UNC13B,
DEAF1,
KAT5,
GLRX3,
DCTN2,
LAMTOR5,
PROCR,
AGR2,
CXCL13,
RABAC1
|
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员