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2893 GRIA4

2893

GRIA4

glutamate ionotropic receptor AMPA type subunit 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition glutamate ionotropic receptor AMPA type subunit 4

研究结论

Date Results Publications
2019-04-06 10:06:00 Study identifies glutamate ionotropic receptor GRIA4 as a risk gene for comorbid nicotine dependence and major depression. 30287806
2018-01-06 11:57:00 The authors suggest that pathogenic de novo variants in GRIA4 lead to intellectual disability with or without seizures, gait abnormalities, problems of social behavior, and other variable features. 29220673
2017-07-29 12:31:00 Study shows that alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor subunit GluA4 is expressed on oligodendrocytes, myelin and on axons in humans. 27443784
2016-05-21 12:37:00 A transient positive feedback mechanism between AMPAR and stargazin has implications for information processing in the brain, because it should allow activity-dependent facilitation of excitatory synaptic transmission through a postsynaptic mechanism. 26744192
2016-01-30 10:59:00 This study demonstrated that the GRIA4 protein was altered in auditory cortex patient with schizophreia. 25433904

名称对应

Type IDs
Synonymous GLUR4, GLUR4C, GLURD, GluA4, NEDSGA
Gene
UniProtKB-ID: GRIA4_HUMAN, Q1WWK6_HUMAN
UniprotKB: P48058, Q1WWK6
UniParc: UPI00006EA6F1, UPI000000DAE2, UPI000013DCE6
EMBL: BC114549, AP000813, U16129, BC045546, AP000673, AP001561, BC142654, AP000641, BC150209
Ensembl: ENSG00000152578
KO: hsa:2893
Nucleutide sequences
EMBL-CDS: AAI42655.1, AAA95962.1, AAI50210.1, AAH45546.1, AAI14550.1
Ensembl_TRS: ENST00000393125, ENST00000530497, ENST00000282499, ENST00000428631
Protein sequencees
Ensembl_PRO: ENSP00000415551, ENSP00000376833, ENSP00000282499, ENSP00000435775
RefSeq: XP_016873100.1, XP_011541079.1, NP_001106283.1, XP_006718886.1, NP_001070711.3, XP_016873099.1, NP_001070712.1, XP_024304223.1, XP_011541078.1, XP_024304222.1, NP_000820.4, XP_005271575.1, XP_011541077.1, XP_016873098.1
Others
UniRef100: UniRef100_P48058, UniRef100_Q1WWK6
UniRef90: UniRef90_P19493
UniRef50: UniRef50_P19493
UniGene: Hs.503743
CCDS: CCDS8333.1, CCDS41707.1

全选

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