| Type | Description |
|---|---|
| Definition | glutamate ionotropic receptor AMPA type subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:03:00 | Emerging role of AMPA receptor subunit GluA1 in synaptic plasticity: Implications for Alzheimer's disease. | 33188547 |
| 2021-01-16 15:53:00 | Amygdala levels of the GluA1 subunit of glutamate receptors and its phosphorylation state at serine 845 in the anterior hippocampus are biomarkers of ictal fear but not anxiety. | 29880883 |
| 2020-05-16 12:20:00 | these data demonstrate that M1 receptor activation induces membrane insertion of GluA1 via a signaling linking and PI3K-Akt-mTOR pathways but is irrelevant to protein synthesis. | 30794430 |
| 2020-03-28 11:32:00 | Nanoscale mobility of resting AMPA receptors predetermines responsiveness to neurotransmitter, allosteric anions and auxiliary subunits. Mobility at rest is regulated by alternative splicing of the flip/flop cassette of the ligand-binding domain, which controls motions in the distant AMPA receptor N-terminal domain (NTD). | 31053408 |
| 2019-10-19 11:01:00 | These findings suggest that AKAP79, by orchestrating phosphorylation, represents a key to a GluA1 phosphorylation passcode, which allows the GluA1 subunit to escape GluA2 dominance and promote the appearance of CP-AMPARs. | 30737285 |
| Type | IDs |
|---|---|
| Synonymous | GLUH1, GLUR1, GLURA, GluA1, HBGR1 |
| Gene |
UniProtKB-ID:
GRIA1_HUMAN,
Q59GL5_HUMAN
UniprotKB:
P42261,
Q59GL5
UniParc:
UPI0000D9B712,
UPI0001E8F433,
UPI00004F6B7E,
UPI000191543D,
UPI0001914C0E,
UPI000020D03D,
UPI000013DE17
EMBL:
AC025156,
AK295039,
AC091960,
BC111734,
AC091962,
AK295827,
M64752,
AC010613,
AB209094,
AK315934,
M81886,
CH471062,
X58633,
AK295184
Ensembl:
ENSG00000155511
KO:
hsa:2890
|
| Nucleutide sequences |
EMBL-CDS:
BAH12192.1,
BAH11956.1,
AAI11735.1,
AAA58613.1,
CAA41491.1,
BAH12004.1,
AAA58395.1,
BAH14305.1,
EAW61650.1,
EAW61649.1,
BAD92331.1
Ensembl_TRS:
ENST00000518783,
ENST00000340592,
ENST00000518142,
ENST00000521843,
ENST00000448073,
ENST00000285900
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000415569,
ENSP00000339343,
ENSP00000427864,
ENSP00000285900,
ENSP00000428994,
ENSP00000427920
RefSeq:
NP_001244949.1,
NP_001244951.1,
NP_001244948.1,
NP_001244952.1,
XP_016864881.1,
NP_001351095.1,
NP_001351096.1,
NP_001244950.1,
NP_001351094.1,
NP_001107655.1,
NP_000818.2
|
| Others |
UniRef100:
UniRef100_P42261,
UniRef100_Q59GL5
UniRef90:
UniRef90_P19490
UniRef50:
UniRef50_P19490
UniGene:
Hs.519693,
Hs.737709
CCDS:
CCDS4322.1,
CCDS47318.1,
CCDS58987.1,
CCDS58989.1,
CCDS58986.1,
CCDS58988.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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