Pgam5 - PGAM family member 5, mitochondrial serine/threonine protein phosphatase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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288731 Pgam5

基因描述

Type	Description
Definition	PGAM family member 5, mitochondrial serine/threonine protein phosphatase

研究结论

Date	Results	Publications
2017-04-01 12:12:00	PGAM5 controls cardiomyocyte apoptosis induced by MIRI through regulating Keap1-mediated Bcl-xL degradation, which may supply a novel molecular target for acute myocardial infarction (AMI) therapy.	27815660

名称对应

Type	IDs
Synonymous	RGD1312028
Gene	UniProtKB-ID: PGAM5_RAT UniprotKB: Q562B5 UniParc: UPI0000505651 EMBL: BC092607 KO: rno:288731
Nucleutide sequences	EMBL-CDS: AAH92607.1
Protein sequencees	RefSeq: XP_006249596.1, NP_001020443.1
Others	UniRef100: UniRef100_Q562B5 UniRef90: UniRef90_Q8BX10 UniRef50: UniRef50_Q8BX10 UniGene: Rn.23489

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
29476059	Identification and characterization of the BRI2 interactome in the brain. Sci Rep Filipa Martins , Ana M Marafona , CÃ¡tia D Pereira , Thorsten MÃ¼ller , Christina Loosse , Katharina Kolbe , Odete A B da Cruz E Silva , Sandra Rebelo	2018-02-23	-
27815660	Mitochondrial phosphatase PGAM5 regulates Keap1-mediated Bcl-xL degradation and controls cardiomyocyte apoptosis driven by myocardial ischemia/reperfusion injury. In Vitro Cell. Dev. Biol. Anim. Chen Yang , Xiaojuan Liu , Fangfang Yang , Weixun Zhang , Zihao Chen , Daliang Yan , Qingsheng You , Xiang Wu	2017-03-01	-
27077115	The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress. EBioMedicine Shiori Sekine , Akari Yao , Kazuki Hattori , Sho Sugawara , Isao Naguro , Masato Koike , Yasuo Uchiyama , Kohsuke Takeda , Hidenori Ichijo	2016-03-01	-
25840011	Selective removal of mitochondria via mitophagy: distinct pathways for different mitochondrial stresses. Biochim. Biophys. Acta Huifang Wei , Lei Liu , Quan Chen	2015-10-01	Csnk2a1, Bnip3l, Pgam5, Pink1, Csnk2a2, Atg7, Ulk1, Fundc1, Park2, Csnk2b, Src, Bnip3
25002582	Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion. J. Biol. Chem. Sushant Bhatnagar , Mufaddal S Soni , Lindsay S Wrighton , Alexander S Hebert , Amber S Zhou , Pradyut K Paul , Trillian Gregg , Mary E Rabaglia , Mark P Keller , Joshua J Coon , Alan D Attie	2014-09-05	-
24647116	The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Trends Biochem Sci John D Hayes , Albena T Dinkova-Kostova	2014-04-01	-
22265414	The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell Zhigao Wang , Hui Jiang , She Chen , Fenghe Du , Xiaodong Wang	2012-01-20	-
19590015	Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1. Proc. Natl. Acad. Sci. U.S.A. Kohsuke Takeda , Yoshiko Komuro , Teruyuki Hayakawa , Haruka Oguchi , Yosuke Ishida , Shiori Murakami , Takuya Noguchi , Hideyuki Kinoshita , Yusuke Sekine , Shun-ichiro Iemura , Tohru Natsume , Hidenori Ichijo	2009-07-28	Pgam5, Ask1, PGAM5, MAP3K5
12477932	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team	2002-12-24	-

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