| Type | Description |
|---|---|
| Definition | growth factor receptor bound protein 7 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:31:00 | Growth factor receptor bound protein-7 regulates proliferation, cell cycle, and mitochondrial apoptosis of thyroid cancer cells via MAPK/ERK signaling. | 32577949 |
| 2020-12-19 13:39:00 | GRB7 is an oncogenic driver and potential therapeutic target in oesophageal adenocarcinoma. | 32737994 |
| 2020-06-20 12:29:00 | In vitro phosphorylation of the Grb7SH2 domain indicates only one of the available tyrosine residues is phosphorylated, suggesting the same phosphorylation pattern could be relevant in the full length protein. | 31353673 |
| 2020-01-11 11:50:00 | this is a review about the molecular, functional, and clinical aspects of Grb7 in erythroblastic leukemia viral oncogene homolog family-mediated cancer family-mediated cancer development and malignancy with the aim to reveal alternative and effective therapeutic strategies.[review] | 31083325 |
| 2019-08-24 10:56:00 | It was identified that silencing of miR193a3p through hypermethylation can promote HER2 positive breast cancer progress by targeting GRB7, ERK1/2 and FOXM1 signaling. | 31017268 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GRB7_HUMAN,
A0A0S2Z4F6_HUMAN
UniprotKB:
Q14451,
A0A0S2Z4F6
UniParc:
UPI000013D841,
UPI000013EE4C,
UPI00021D6334,
UPI0001AE662D
EMBL:
AB008790,
AK125544,
AK314368,
AK290115,
AC079199,
BT006686,
D87513,
KU178103,
AK222849,
AK222870,
D43772,
CH471152,
BC006535,
AB008789,
AF274875,
AK027729
Ensembl:
ENSG00000141738
KO:
hsa:2886
|
| Nucleutide sequences |
EMBL-CDS:
BAG51372.1,
BAA29060.1,
BAF82804.1,
EAW60600.1,
AAG25938.1,
AAP35332.1,
BAD96569.1,
BAA13412.1,
BAG54211.1,
BAG36998.1,
AAH06535.1,
BAD96590.1,
BAA29059.1,
EAW60601.1,
BAA07827.1,
ALQ33561.1
Ensembl_TRS:
ENST00000394211,
ENST00000445327,
ENST00000394209,
ENST00000309156,
ENST00000394204
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000377759,
ENSP00000403459,
ENSP00000310771,
ENSP00000377754,
ENSP00000377761
RefSeq:
NP_001317136.1,
XP_024306497.1,
NP_001229372.1,
NP_005301.2,
NP_001229371.2,
NP_001025173.1
|
| Others |
UniRef100:
UniRef100_Q14451
UniRef90:
UniRef90_Q14451
UniRef50:
UniRef50_Q14451
UniGene:
Hs.86859
CCDS:
CCDS82116.1,
CCDS11345.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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