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288227 Bace2

288227

Bace2

beta-secretase 2

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition beta-secretase 2

研究结论

Date Results Publications
2015-05-02 12:57:00 found by global gene expression profiling that BACE2 was up-regulated in the rat pancreatic beta-cell line INS1E stably transfected with human IAPP gene 25342134
2011-06-04 10:51:00 Data show that astrocytes possess beta-secretase activity and produce amyloid-beta because of the activity of BACE2, but not BACE1, the expression of which is blocked at the translational level. 21073551
2010-01-21 00:00:00 Results describe the functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells. 16757811
2010-01-21 00:00:00 The presence of BACE2 in secretory granules of beta cells suggests that it may play a role in diabetes-associated amyloidogenesis. 19117266

名称对应

Type IDs
Gene
UniProtKB-ID: BACE2_RAT
UniprotKB: Q6IE75
UniParc: UPI00003B3255
EMBL: BN000318, BC166597
Ensembl: ENSRNOG00000001953
KO: rno:288227
Nucleutide sequences
EMBL-CDS: AAI66597.1, CAE48373.1
Ensembl_TRS: ENSRNOT00000002679
Protein sequencees
Ensembl_PRO: ENSRNOP00000002679
RefSeq: NP_001002802.1
Others
UniRef100: UniRef100_Q6IE75
UniRef90: UniRef90_Q9JL18
UniRef50: UniRef50_Q9Y5Z0
UniGene: Rn.38581

全选

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研究热度

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