Abr - ABR, RhoGEF and GTPase activating protein-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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287537 Abr

基因描述

Type	Description
Definition	ABR, RhoGEF and GTPase activating protein

研究结论

Date	Results	Publications
2010-11-27 10:45:00	breakpoint cluster region and ABR have novel roles in the regulation of synaptic Rac1 signaling, synaptic plasticity, and learning and memory, and that excessive Rac1 activity negatively affects synaptic and cognitive functions	20962234

名称对应

Type	IDs
Gene	UniProtKB-ID: ABR_RAT UniprotKB: A0A0G2JTR4 UniParc: UPI0000251575 EMBL: AABR07072152, FQ078152.1, AABR07030047 KO: rno:287537
Nucleutide sequences
Protein sequencees	RefSeq: NP_001099284.1
Others	UniRef100: UniRef100_A0A0G2JTR4 UniRef90: UniRef90_Q5SSL4 UniRef50: UniRef50_Q5SSL4 UniGene: Rn.44897

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
23152932	Lack of bcr and abr promotes hypoxia-induced pulmonary hypertension in mice. PLoS One Min Yu , Dapeng Gong , Min Lim , Anna Arutyunyan , John Groffen , Nora Heisterkamp	2012-01-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
20962234	Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins. J. Neurosci. Daeyoung Oh , Seungnam Han , Jinsoo Seo , Jae-Ran Lee , Jeonghoon Choi , John Groffen , Karam Kim , Yi Sul Cho , Han-Saem Choi , Hyewon Shin , Jooyeon Woo , Hyejung Won , Soon Kwon Park , Soo-Young Kim , Jihoon Jo , Daniel J Whitcomb , Kwangwook Cho , Hyun Kim , Yong Chul Bae , Nora Heisterkamp , Se-Young Choi , Eunjoon Kim	2010-10-20	Abr, Bcr, Abr, Bcr, Rac1
19946888	Defining the membrane proteome of NK cells. J Mass Spectrom Dhimankrishna Ghosh , Dustin Lippert , Oleg Krokhin , John P Cortens , John A Wilkins	2010-01-01	MED6, PDCD6IP, MED16, PIGK, DNAJB6, FARSB, DNM1L, ABCF2, HUWE1, ARPC3, ACTR3, ACTR2, RAD50, PREB, ACTR1B, LRPPRC, TRAP1, BCAP31, PLXNC1, LPCAT3, TNK2, PSME3, MPHOSPH9, FLOT1, DDX39A, AK6, ADAM10, PLIN3, CALCOCO2, CDK9, ABCC4, ZMPSTE24, AKAP8, BET1, MARCH6, KATNB1, ADAR, EMC8, BTN3A3, ATP8A1, NDC80, CDIPT, PGRMC2, TUBGCP3, ECI2, COG5, SLC25A17, LRRC41, SYNCRIP, MYBBP1A, DDX17, CHERP, HYOU1, IPO7, NOP56, ARL6IP5, HTATIP2, AGPAT1, ARFGEF2, RABAC1, SLU7, PRPF8, PAICS, CENPE, PMVK, KHDRBS1, CELF1, GNA13, CFL1, MGEA5, YME1L1, STAG2, CTSC, GIPC1, HBS1L, TUBGCP2, PGRMC1, MAN1A2, PNPLA6, MAGED2, ADCY3, EHD1, TOMM34, ERP29, YWHAQ, ASCC3, GCN1, IMMT, ILVBL, SLC27A4, SLC27A3, KIF2C, GLIPR1, CPSF6, DDX52, WWP2, CNTRL, CHD4, KRR1
19703997	Bcr and Abr cooperate in negatively regulating acute inflammatory responses. Mol Cell Biol Jess M Cunnick , Sabine Schmidhuber , Gang Chen , Min Yu , Sun-Ju Yi , Young Jin Cho , Vesa Kaartinen , Parviz Minoo , David Warburton , John Groffen , Nora Heisterkamp	2009-11-01	-
17116687	Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages. Mol. Cell. Biol. Young Jin Cho , Jess M Cunnick , Sun-Ju Yi , Vesa Kaartinen , John Groffen , Nora Heisterkamp	2007-02-01	Abr, Bcr, Rac1
11921339	Vestibular dysgenesis in mice lacking Abr and Bcr Cdc42/RacGAPs. Dev. Dyn. Vesa Kaartinen , Andre Nagy , Ignacio Gonzalez-Gomez , John Groffen , Nora Heisterkamp	2002-04-01	Abr, Bcr, ABR
11684658	Abnormal function of astroglia lacking Abr and Bcr RacGAPs. Development V Kaartinen , I Gonzalez-Gomez , J W Voncken , L Haataja , E Faure , A Nagy , J Groffen , N Heisterkamp	2001-11-01	Abr, Bcr
7479768	Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family. Proc. Natl. Acad. Sci. U.S.A. T H Chuang , X Xu , V Kaartinen , N Heisterkamp , J Groffen , G M Bokoch	1995-10-24	-

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