| Type | Description |
|---|---|
| Definition | arachidonate 12-lipoxygenase, 12S type |
| Date | Results | Publications |
|---|---|---|
| 2017-08-26 11:02:00 | Angiotensin II type 1 receptor blocker potentially ameliorates diabetic nephropathy via the up-regulation of glomerular nephrin and P-cadherin expression through the inhibition of 12-LO activation in the glomeruli of rats with type 2 diabetes. | 27021232 |
| 2017-04-08 10:48:00 | The aim of the present study was to examine the impacts and mechanisms of 12lipoxygenase (12LO) and its metabolites on the acetylation and methylation of histone3lysine (H3K) in the p21 gene. associated epigenetic changes, including increased histone H3K9Ac and H3K4Me1, and reduced H3K9M.e3 may involved in 12 (S)hydroxyeicosatetraenoic acid mediated p21 gene regulation. | 27600103 |
| 2015-01-03 10:42:00 | Hypoxic preconditioning reduces heart susceptibly to ischemia-reperfusion injuryvia pathway. | 24816396 |
| 2011-06-04 10:58:00 | Diabetic proteinuria is mediated by the activation of 12-LO pathway that is partially attributed to the decreased glomerular P-cadherin expression. | 21285403 |
| 2010-01-21 00:00:00 | Role of Src tyrosine kinase in the atherogenic effects of the 12/15-lipoxygenase pathway in vascular smooth muscle cells. | 19095999 |
| Type | IDs |
|---|---|
| Synonymous | 12-LO, 12S-LOX |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
NP_001099268.2,
XP_006246721.1
|
| Others |
UniGene:
Rn.66513
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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