| Type | Description |
|---|---|
| Definition | period circadian regulator 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-23 11:06:00 | This study demonstrated that optimal auditory conditioned fear extinction learning is reliant on the presence of normal per1 gene expression in the vmPFC as well as the presence of both circadian and training-associated elevations of glucocorticoid hormone | 30627637 |
| 2019-01-05 10:45:00 | Restraint stress increased Per1 mRNA in the hypothalamic paraventricular nucleus and prefrontal cortex of both sexes. | 29165002 |
| 2018-02-10 11:06:00 | Sequential and tandem ChIP analyses showed that, after forced swim (FS) stress , MRs and GRs bind concomitantly to the same GRE sites within Fkbp5 and Per1 but not Sgk1 Thus, after stress, MRs and GRs seem to bind to GREs as homo- and/or heterodimers in a gene-dependent manner. MR binding to GREs at baseline seems to be restricted, whereas after stress, GR binding may facilitate cobinding of MR | 27655894 |
| 2018-01-13 14:49:00 | Report altered expression pattern of clock genes, Per1, Per2 and Bmal1, in sub-oscillators of the rat brain and in the liver in rat model of depression. | 27365111 |
| 2017-07-22 12:26:00 | Study demonstrates that transcriptional activation of Per1 and Per2 via E-box enhancer sequences is necessary for the temporally specific phase shifts induced by melatonin at circadian time 10. These findings support a link between melatonin-induced signal transduction pathways activating necessary Per1 and Per2 transcription and clock resetting in the suprachiasmatic nucleus by melatonin at dusk. | 27362940 |
| Type | IDs |
|---|---|
| Synonymous | rper1 |
| Gene |
UniProtKB-ID:
PER1_RAT
UniprotKB:
Q8CHI5
UniParc:
UPI000021D5CA
EMBL:
AY903229,
AY903228,
AB092976,
AY903230
KO:
rno:287422
|
| Nucleutide sequences |
EMBL-CDS:
AAX85359.1,
AAX85358.1,
AAX85360.1,
BAC53666.1
|
| Protein sequencees |
RefSeq:
XP_006246675.1,
NP_001029297.1,
XP_006246676.1
|
| Others |
UniRef100:
UniRef100_Q8CHI5
UniRef90:
UniRef90_Q8CHI5
UniRef50:
UniRef50_O35973
UniGene:
Rn.34433
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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