| Type | Description |
|---|---|
| Definition | mitogen activated protein kinase kinase 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 10:47:00 | Findings indicated that miR-27a-3p inhibitor protected against epilepsy-induced inflammatory response and hippocampal neuronal apoptosis by targeting MAP2K4. | 31710596 |
| 2018-07-07 10:54:00 | MKK4 overexpression enhanced TNF-alpha-mediated signaling activation and transcription of downstream catabolic genes, and consequently worsened cartilage degradation. | 29072705 |
| 2014-11-22 13:01:00 | Demonstrate that Mkk4 is a negative regulator of the TGF-beta1 signaling associated with atrial remodeling and arrhythmogenesis with age. | 24721794 |
| 2012-01-28 10:31:00 | These data support a model in which MKK4 activation at the metastatic site causes a cell-cycle arrest. | 21351092 |
| 2011-12-06 12:04:00 | SGK1 negatively regulates stress-activated signaling through inhibition of SEK1 function. | 17568772 |
| Type | IDs |
|---|---|
| Synonymous | MKK4, Sek1 |
| Gene |
UniProtKB-ID:
Q4KSH6_RAT
UniprotKB:
Q4KSH6
UniParc:
UPI0000003FFD
EMBL:
AY880882
KO:
rno:287398
|
| Nucleutide sequences |
EMBL-CDS:
AAX61181.1
|
| Protein sequencees |
RefSeq:
NP_001025194.1
|
| Others |
UniRef100:
UniRef100_P47809
UniRef90:
UniRef90_P47809
UniRef50:
UniRef50_P45985
UniGene:
Rn.198875
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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