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2873 GPS1

2873

GPS1

G protein pathway suppressor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition G protein pathway suppressor 1

研究结论

Date Results Publications
2017-07-22 13:08:00 We identified recurrent mutations in the novel penile cancer tumor suppressor genes CSN1(GPS1) and FAT1 27325650
2016-12-31 10:04:00 CSN1 appears to play a role not only in DNA repair but also in UV-induced apoptosis. 26986008
2013-06-15 12:05:00 We analyzed whether CSN1 alone can increase DEN1 degradation in HeLa cells.these data suggest that the COP9 signalosome supports proteasome-dependent protein degradation of DEN1/DenA in fungi and in human cells. 23408908
2012-09-15 11:31:00 An increased level of CSN1 and CSN5 as an important part of the ubiquitin proteasome system (UPS) might be associated with the pathophysiology of preeclampsia. 22103747
2011-10-01 12:08:00 CSN1 inhibits c-Jun phosphorylation without affecting its protein stability. 21604193

名称对应

Type IDs
Synonymous COPS1, CSN1, SGN1
Gene
UniProtKB-ID: CSN1_HUMAN, A0A096LP07_HUMAN, A0A096LPJ3_HUMAN, C9JFE4_HUMAN
UniprotKB: Q13098, A0A096LP07, A0A096LPJ3, C9JFE4
UniParc: UPI000013EB91, UPI00004650AA, UPI00021DE654, UPI0000D4D767, UPI0000D4D04F, UPI0000128555, UPI0000231C2E
EMBL: BC000155, BC064503, CH471099, U20285, AC135056, BT009834, AK093283
Ensembl: ENSG00000169727
KO: hsa:2873
Nucleutide sequences
EMBL-CDS: AAH00155.3, AAP88836.1, BAC04120.1, AAH64503.1, AAC50906.2, EAW89742.1
Gene_ORFName: hCG_1987516
Ensembl_TRS: ENST00000306823, ENST00000578552, ENST00000392358, ENST00000623691, ENST00000624957, ENST00000320548
Protein sequencees
Ensembl_PRO: ENSP00000376167, ENSP00000462265, ENSP00000302873, ENSP00000485330, ENSP00000485641, ENSP00000313569
RefSeq: XP_024306494.1, XP_024306495.1, XP_005256407.1, XP_024306481.1, NP_001308022.1, NP_997657.1, NP_001308018.1, XP_016880013.1, XP_016880024.1, XP_024306483.1, XP_024306487.1, NP_001317470.1, XP_024306490.1, XP_016880014.1, XP_024306492.1, XP_024306488.1, XP_005256410.1, XP_024306485.1, XP_016880023.1, NP_001317468.1, XP_024306489.1, NP_001308020.1, XP_005256417.1, NP_004118.3, XP_005256416.1, XP_024306493.1, NP_001308019.1, XP_024306496.1, XP_016880015.1, XP_024306486.1, XP_016880020.1, XP_024306484.1, XP_024306491.1, XP_016880016.1, XP_024306482.1, NP_001308021.1
Others
UniRef100: UniRef100_C9JFE4, UniRef100_A0A096LP07, UniRef100_Q13098, UniRef100_A0A096LPJ3
UniRef90: UniRef90_A0A096LP07, UniRef90_Q13098, UniRef90_C9JFE4
UniRef50: UniRef50_Q13098, UniRef50_C9JFE4
UniGene: Hs.268530
CCDS: CCDS32774.1, CCDS11800.1, CCDS82226.1

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