| Type | Description |
|---|---|
| Definition | G protein-coupled receptor kinase 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 11:13:00 | GRK6 S-nitrosylation at cys 474 enhances its kinase activity toward alpha-syn phosphorylation at S129. | 32343709 |
| 2019-11-23 12:42:00 | MiR-19b-3p attenuates IL-1beta induced extracellular matrix degradation and inflammatory injury in chondrocytes by targeting GRK6. | 31227976 |
| 2019-11-16 12:15:00 | Hypermethylation of the GRK6 gene promoter suppressed binding of C/EBPalpha, thereby contributing to the promotion of cell migration and invasion. | 30984536 |
| 2018-10-06 10:54:00 | GRK6 overexpression can significantly enhance tumor proliferation and invasion, which was consistent with clinical findings. | 29805156 |
| 2017-11-04 10:50:00 | demonstrate for the first time exosomal enrichment of G-protein-coupled receptor kinase (GRK) 5 and GRK6, both of which regulate Src and IGF-IR signaling and have been implicated in cancer. | 27232975 |
| Type | IDs |
|---|---|
| Synonymous | GPRK6 |
| Gene |
UniProtKB-ID:
GRK6_HUMAN,
B3KPS5_HUMAN
UniprotKB:
P43250,
B3KPS5
UniParc:
UPI000012BADE,
UPI0000371A0E,
UPI000002AAC9,
UPI000013FD9D
EMBL:
U00686,
AK056697,
AF040751,
AF040752,
L16862,
AC145098,
BC009277
Ensembl:
ENSG00000198055
KO:
hsa:2870
|
| Nucleutide sequences |
EMBL-CDS:
AAC09273.1,
AAA60175.1,
AAA03565.1,
AAH09277.1,
AAC09274.1,
BAG51787.1
Ensembl_TRS:
ENST00000355958,
ENST00000355472,
ENST00000528793
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000347655,
ENSP00000433511,
ENSP00000348230
RefSeq:
XP_006714921.1,
XP_006714922.1,
NP_001351093.1,
XP_024301800.1,
XP_011532839.1,
NP_001004105.1,
XP_011532840.1,
NP_002073.2,
NP_001004106.1
|
| Others |
UniRef100:
UniRef100_B3KPS5,
UniRef100_P43250
UniRef90:
UniRef90_P43250
UniRef50:
UniRef50_P43250
UniGene:
Hs.235116
CCDS:
CCDS34303.1,
CCDS43406.1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
Howard Hughes Medical Institute |
7 |
| 2 |
Duke University Medical Center |
4 |
| 3 |
Thomas Jefferson University |
3 |
| 4 |
National Cancer Institute |
2 |
| 5 |
College of Pharmacy |
2 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
J L Benovic |
7 |
| 2 |
R J Lefkowitz |
7 |
| 3 |
R T Premont |
6 |
| 4 |
R H Stoffel |
3 |
| 5 |
Jeffrey L Benovic |
3 |