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2870 GRK6

2870

GRK6

G protein-coupled receptor kinase 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition G protein-coupled receptor kinase 6

研究结论

Date Results Publications
2020-07-25 11:13:00 GRK6 S-nitrosylation at cys 474 enhances its kinase activity toward alpha-syn phosphorylation at S129. 32343709
2019-11-23 12:42:00 MiR-19b-3p attenuates IL-1beta induced extracellular matrix degradation and inflammatory injury in chondrocytes by targeting GRK6. 31227976
2019-11-16 12:15:00 Hypermethylation of the GRK6 gene promoter suppressed binding of C/EBPalpha, thereby contributing to the promotion of cell migration and invasion. 30984536
2018-10-06 10:54:00 GRK6 overexpression can significantly enhance tumor proliferation and invasion, which was consistent with clinical findings. 29805156
2017-11-04 10:50:00 demonstrate for the first time exosomal enrichment of G-protein-coupled receptor kinase (GRK) 5 and GRK6, both of which regulate Src and IGF-IR signaling and have been implicated in cancer. 27232975

名称对应

Type IDs
Synonymous GPRK6
Gene
UniProtKB-ID: GRK6_HUMAN, B3KPS5_HUMAN
UniprotKB: P43250, B3KPS5
UniParc: UPI000012BADE, UPI0000371A0E, UPI000002AAC9, UPI000013FD9D
EMBL: U00686, AK056697, AF040751, AF040752, L16862, AC145098, BC009277
Ensembl: ENSG00000198055
KO: hsa:2870
Nucleutide sequences
EMBL-CDS: AAC09273.1, AAA60175.1, AAA03565.1, AAH09277.1, AAC09274.1, BAG51787.1
Ensembl_TRS: ENST00000355958, ENST00000355472, ENST00000528793
Protein sequencees
Ensembl_PRO: ENSP00000347655, ENSP00000433511, ENSP00000348230
RefSeq: XP_006714921.1, XP_006714922.1, NP_001351093.1, XP_024301800.1, XP_011532839.1, NP_001004105.1, XP_011532840.1, NP_002073.2, NP_001004106.1
Others
UniRef100: UniRef100_B3KPS5, UniRef100_P43250
UniRef90: UniRef90_P43250
UniRef50: UniRef50_P43250
UniGene: Hs.235116
CCDS: CCDS34303.1, CCDS43406.1

全选

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