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286940 Flnb

286940

Flnb

filamin, beta

protein-coding

Mus musculus

基因描述

Type Description
Definition filamin, beta

研究结论

Date Results Publications
2018-12-22 12:12:00 this study finds highest filamin B editing levels in skeletal muscles, cartilage and bones, tissues where Filamin B function seems most important. 30064337
2016-08-13 12:18:00 These findings indicate that FLNB is involved in attenuation of TGFb/BMP signaling and influences annulus fibrosus cell fate 27019229
2015-04-04 10:51:00 Fmn1 and FlnB have shared and independent functions. 24760772
2015-01-17 11:35:00 Filamin a, b-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeleton. 24436304
2014-10-25 12:42:00 FlnB loss reduced Cdk1 phosphorylation (an inhibitor of G2/M phase progression) and Cdk1 inhibition in chondrocytes mimicked the null FlnB, premature differentiation phenotype, through a beta1-integrin receptor- Pi3k/Akt mediated pathway. 24551245

名称对应

Type IDs
Synonymous AL024016, Fln-b
Gene
UniProtKB-ID: FLNB_MOUSE
UniprotKB: Q80X90
UniParc: UPI00006070DD
EMBL: BC003959, AC140322, BC048835, AF353672, AF353669, AC129222
Ensembl: ENSMUSG00000025278
KO: mmu:286940
Nucleutide sequences
EMBL-CDS: AAH03959.1, AAH48835.1, AAL68448.1, AAL68445.1
Ensembl_TRS: ENSMUST00000052678
Protein sequencees
Ensembl_PRO: ENSMUSP00000052020
RefSeq: NP_598841.1, XP_006518113.1, NP_001074896.1
Others
UniRef100: UniRef100_Q80X90
UniRef90: UniRef90_Q80X90
UniRef50: UniRef50_O75369
UniGene: Mm.489652
CCDS: CCDS70540.1

全选

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研究热度

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