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286410 ATP11C

286410

ATP11C

ATPase phospholipid transporting 11C

protein-coding

Homo sapiens

基因描述

Type Description
Definition ATPase phospholipid transporting 11C

研究结论

Date Results Publications
2021-01-16 15:54:00 Crystal structure of a human plasma membrane phospholipid flippase. 32493773
2020-08-15 19:03:00 The cytoplasmic C-terminal region of the ATP11C variant determines its localization at the polarized plasma membrane. 31371488
2020-07-11 11:27:00 Data show that P4-ATPase flippase complex alpha subunit ATP11C (ATP11C) was absent in the patient's erythrocyte membranes. 31253392
2018-12-22 10:13:00 results indicated that the extracellular domain of CDC50A has important roles both in CDC50A's ability to chaperone ATP11C to the plasma membrane and in inducing ATP11C's ATP hydrolysis-coupled flippase activity. 29276178
2018-09-22 10:17:00 A characteristic di-leucine motif (SVRPLL) in the C-terminal cytoplasmic region of ATP11C becomes functional upon activation. Moreover, endocytosis of ATP11C is induced by Ca(2+)-signaling via Gq-coupled receptors. 29123098

名称对应

Type IDs
Synonymous ATPIG, ATPIQ, HACXL
Gene
UniProtKB-ID: AT11C_HUMAN
UniprotKB: Q8NB49
UniParc: UPI000036777E, UPI00004F6EED, UPI00004F6EEB, UPI00004F6EEC
EMBL: AK125986, AK091552, AJ580094, AL590077, AK125474, AL356785, AL161777, AK131262, AJ580093
Ensembl: ENSG00000101974
KO: hsa:286410
Nucleutide sequences
EMBL-CDS: BAC86377.1, CAE30473.1, BAD18440.1, BAC86172.1, CAE30472.1, BAC03692.1
Ensembl_TRS: ENST00000327569, ENST00000361648
Protein sequencees
Ensembl_PRO: ENSP00000332756, ENSP00000355165
RefSeq: NP_001340740.2, XP_016884937.1, XP_016884935.1, XP_016884938.1, XP_016884931.1, XP_016884930.1, NP_001340741.2, NP_001340739.2, XP_016884934.1, XP_016884928.1, XP_016884932.1, XP_016884929.1, NP_775965.3, NP_001010986.2
Others
UniRef100: UniRef100_Q8NB49
UniRef90: UniRef90_Q8NB49
UniRef50: UniRef50_Q8NB49
UniGene: Hs.88252
CCDS: CCDS14668.1, CCDS35410.1

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