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286205 SCAI

286205

SCAI

suppressor of cancer cell invasion

protein-coding

Homo sapiens

基因描述

Type Description
Definition suppressor of cancer cell invasion

研究结论

Date Results Publications
2021-04-17 13:12:00 miR-371b-5p promotes cell proliferation, migration and invasion in non-small cell lung cancer via SCAI. 33103723
2020-07-25 12:08:00 MicroRNA-625-3p was highly expressed in oral squamous cell carcinoma (OSCC) tissues. OSCC patients with T3+T4 stage had higher expression of microRNA-625-3p than those with T1+T2 stage. SCAI was identified as a target gene of microRNA-625-3p. ROC curve showed that microRNA-625-3p and SCAI exert certain values in diagnosing OSCC. MicroRNA-625-3p promoted migration of OSCC cells, which was reversed by SCAI knockdown. 30720172
2020-03-21 10:06:00 This study provides evidence that CAF exosomal miR-1228 is able to promote osteosarcoma invasion and migration by targeting SCAI. 30180920
2019-04-06 12:07:00 SCAI binds to miR-1270 which inversely regulates SCAI gene expression in papillary thyroid cancer cells. 30551495
2018-10-27 10:03:00 High SCAI expression is associated with gastric, prostate, and colorectal cancer. 28815470

名称对应

Type IDs
Synonymous C9orf126, NET40
Gene
UniProtKB-ID: SCAI_HUMAN
UniprotKB: Q8N9R8
UniParc: UPI000013F2EF, UPI00002117CF
EMBL: AK098024, AL445930, CH471090, BC104031, AL451125, BC104030
Ensembl: ENSG00000173611
KO: hsa:286205
Nucleutide sequences
EMBL-CDS: BAC05217.1, EAW87608.1, EAW87609.1, AAI04032.1, AAI04031.1
Ensembl_TRS: ENST00000336505, ENST00000373549
Protein sequencees
Ensembl_PRO: ENSP00000336756, ENSP00000362650
RefSeq: NP_775961.2, NP_001138349.1
Others
UniRef100: UniRef100_Q8N9R8
UniRef90: UniRef90_Q8N9R8
UniRef50: UniRef50_Q8N9R8
UniGene: Hs.59504
CCDS: CCDS48017.1, CCDS43877.1

全选

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