| Type | Description |
|---|---|
| Definition | SH3 and PX domains 2B |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:16:00 | Enhanced endothelial motility and multicellular sprouting is mediated by the scaffold protein TKS4. | 31591456 |
| 2020-10-10 13:01:00 | Significance of the Tks4 scaffold protein in bone tissue homeostasis. | 30962481 |
| 2020-08-22 15:25:00 | Absence of the Tks4 Induces Epithelial-Mesenchymal Transition-Like Changes in Human Colon | 31671862 |
| 2019-04-06 10:31:00 | The interaction of Tks4 with Src may result in the long term stabilization of the kinase in its active conformation, leading to prolonged Src activity following epidermal growth factor stimulation. | 29928795 |
| 2018-06-16 11:36:00 | We report a sibling pair with Frank-ter Haar syndrome (FTHS) caused by a homozygous, novel mutation pLys133Glnfs*13 in the SH3PXD2B gene. | 29100834 |
| Type | IDs |
|---|---|
| Synonymous | FAD49, FTHS, HOFI, KIAA1295, TKS4, TSK4 |
| Gene |
UniProtKB-ID:
SPD2B_HUMAN,
G3V144_HUMAN
UniprotKB:
A1X283,
G3V144
UniParc:
UPI000020C131,
UPI000020C12E
EMBL:
AC008671,
AC090064,
AB430862,
AC011407,
CH471062,
AB037716,
DQ109556
Ensembl:
ENSG00000174705
KO:
hsa:285590
|
| Nucleutide sequences |
EMBL-CDS:
BAG81977.1,
AAZ99795.1,
BAA92533.1,
EAW61432.1
Gene_ORFName:
hCG_40282
Ensembl_TRS:
ENST00000311601,
ENST00000519643
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000309714,
ENSP00000430890
RefSeq:
NP_001017995.1,
NP_001295104.1,
XP_016864840.1
|
| Others |
UniRef100:
UniRef100_A1X283,
UniRef100_G3V144
UniRef90:
UniRef90_G3V144,
UniRef90_A1X283
UniRef50:
UniRef50_Q6DC19,
UniRef50_A2AAY5
UniGene:
Hs.285666
CCDS:
CCDS34291.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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