| Type | Description |
|---|---|
| Definition | cytochrome c oxidase assembly factor COX18 |
| Date | Results | Publications |
|---|---|---|
| 2017-07-15 10:45:00 | COX20 stabilizes COX2 during insertion of its N-proximal transmembrane domain, and subsequently, COX18 transiently interacts with COX2 to promote translocation across the inner membrane of the COX2 C-tail that contains the apo-CuA site. The release of COX18 from this complex coincides with the binding of the SCO1-SCO2-COA6 copper metallation module to COX2-COX20 to finalize COX2 biogenesis. | 28330871 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | 20819778 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| 2010-04-07 21:39:00 | Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | 20200953 |
| Type | IDs |
|---|---|
| Synonymous | COX18HS |
| Gene |
UniProtKB-ID:
COX18_HUMAN,
B7ZL88_HUMAN
UniprotKB:
Q8N8Q8,
B7ZL88
UniParc:
UPI000006FD5F,
UPI0000EADF1D,
UPI00004918BB,
UPI0000EADF1B,
UPI0000EADF1C
EMBL:
BC143642,
AM055750,
BC071812,
AY957565,
AM055752,
AC095053,
AK096310,
BC101684,
AY957564,
AM055751
Ensembl:
ENSG00000163626
KO:
hsa:285521
|
| Nucleutide sequences |
EMBL-CDS:
AAH71812.1,
CAJ20057.1,
AAY35061.1,
AAY35060.1,
CAJ20055.1,
CAJ20056.1,
AAI01685.1,
BAC04758.1,
AAI43643.1
Ensembl_TRS:
ENST00000510031,
ENST00000295890,
ENST00000449739,
ENST00000507544
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000295890,
ENSP00000424978,
ENSP00000394583,
ENSP00000425261
RefSeq:
NP_776188.1,
NP_001284662.1,
XP_016863534.1,
XP_005265737.1,
XP_011530180.1,
NP_001287658.1,
NP_001284661.1
|
| Others |
UniRef100:
UniRef100_Q8N8Q8,
UniRef100_B7ZL88
UniRef90:
UniRef90_Q8N8Q8
UniRef50:
UniRef50_Q8N8Q8
UniGene:
Hs.356697
CCDS:
CCDS3554.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 28330871 |
J Biol Chem Myriam Bourens , Antoni Barrientos |
2017-05-12 | - |
| 25217961 |
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. Nat. Genet. Ali Amin Al Olama , Zsofia Kote-Jarai , Sonja I Berndt , David V Conti , Fredrick Schumacher , Ying Han , Sara Benlloch , Dennis J Hazelett , Zhaoming Wang , Ed Saunders , Daniel Leongamornlert , Sara Lindstrom , Sara Jugurnauth-Little , Tokhir Dadaev , Malgorzata Tymrakiewicz , Daniel O Stram , Kristin Rand , Peggy Wan , Alex Stram , Xin Sheng , Loreall C Pooler , Karen Park , Lucy Xia , Jonathan Tyrer , Laurence N Kolonel , Loic Le Marchand , Robert N Hoover , Mitchell J Machiela , Merideth Yeager , Laurie Burdette , Charles C Chung , Amy Hutchinson , Kai Yu , Chee Goh , Mahbubl Ahmed , Koveela Govindasami , Michelle Guy , Teuvo L J Tammela , Anssi Auvinen , Tiina Wahlfors , Johanna Schleutker , Tapio Visakorpi , Katri A Leinonen , Jianfeng Xu , Markus Aly , Jenny Donovan , Ruth C Travis , Tim J Key , Afshan Siddiq , Federico Canzian , Kay-Tee Khaw , Atsushi Takahashi , Michiaki Kubo , Paul Pharoah , Nora Pashayan , Maren Weischer , Borge G Nordestgaard , Sune F Nielsen , Peter Klarskov , Martin Andreas Røder , Peter Iversen , Stephen N Thibodeau , Shannon K McDonnell , Daniel J Schaid , Janet L Stanford , Suzanne Kolb , Sarah Holt , Beatrice Knudsen , Antonio Hurtado Coll , Susan M Gapstur , W Ryan Diver , Victoria L Stevens , Christiane Maier , Manuel Luedeke , Kathleen Herkommer , Antje E Rinckleb , Sara S Strom , Curtis Pettaway , Edward D Yeboah , Yao Tettey , Richard B Biritwum , Andrew A Adjei , Evelyn Tay , Ann Truelove , Shelley Niwa , Anand P Chokkalingam , Lisa Cannon-Albright , Cezary Cybulski , Dominika WokoÅorczyk , Wojciech Kluźniak , Jong Park , Thomas Sellers , Hui-Yi Lin , William B Isaacs , Alan W Partin , Hermann Brenner , Aida Karina Dieffenbach , Christa Stegmaier , Constance Chen , Edward L Giovannucci , Jing Ma , Meir Stampfer , Kathryn L Penney , Lorelei Mucci , Esther M John , Sue A Ingles , Rick A Kittles , Adam B Murphy , Hardev Pandha , Agnieszka Michael , Andrzej M Kierzek , William Blot , Lisa B Signorello , Wei Zheng , Demetrius Albanes , Jarmo Virtamo , Stephanie Weinstein , Barbara Nemesure , John Carpten , Cristina Leske , Suh-Yuh Wu , Anselm Hennis , Adam S Kibel , Benjamin A Rybicki , Christine Neslund-Dudas , Ann W Hsing , Lisa Chu , Phyllis J Goodman , Eric A Klein , S Lilly Zheng , Jyotsna Batra , Judith Clements , Amanda Spurdle , Manuel R Teixeira , Paula Paulo , Sofia Maia , Chavdar Slavov , Radka Kaneva , Vanio Mitev , John S Witte , Graham Casey , Elizabeth M Gillanders , Daniella Seminara , Elio Riboli , Freddie C Hamdy , Gerhard A Coetzee , Qiyuan Li , Matthew L Freedman , David J Hunter , Kenneth Muir , Henrik Gronberg , David E Neal , Melissa Southey , Graham G Giles , Gianluca Severi , Breast and Prostate Cancer Cohort Consortium (BPC3) , PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium , COGS (Collaborative Oncological Gene-environment Study) Consortium , GAME-ON/ELLIPSE Consortium , Michael B Cook , Hidewaki Nakagawa , Fredrik Wiklund , Peter Kraft , Stephen J Chanock , Brian E Henderson , Douglas F Easton , Rosalind A Eeles , Christopher A Haiman |
2014-10-01 | - |
| 23535732 |
Nat Genet Rosalind A Eeles , Ali Amin Al Olama , Sara Benlloch , Edward J Saunders , Daniel A Leongamornlert , Malgorzata Tymrakiewicz , Maya Ghoussaini , Craig Luccarini , Joe Dennis , Sarah Jugurnauth-Little , Tokhir Dadaev , David E Neal , Freddie C Hamdy , Jenny L Donovan , Ken Muir , Graham G Giles , Gianluca Severi , Fredrik Wiklund , Henrik Gronberg , Christopher A Haiman , Fredrick Schumacher , Brian E Henderson , Loic Le Marchand , Sara Lindstrom , Peter Kraft , David J Hunter , Susan Gapstur , Stephen J Chanock , Sonja I Berndt , Demetrius Albanes , Gerald Andriole , Johanna Schleutker , Maren Weischer , Federico Canzian , Elio Riboli , Tim J Key , Ruth C Travis , Daniele Campa , Sue A Ingles , Esther M John , Richard B Hayes , Paul D P Pharoah , Nora Pashayan , Kay-Tee Khaw , Janet L Stanford , Elaine A Ostrander , Lisa B Signorello , Stephen N Thibodeau , Dan Schaid , Christiane Maier , Walther Vogel , Adam S Kibel , Cezary Cybulski , Jan Lubinski , Lisa Cannon-Albright , Hermann Brenner , Jong Y Park , Radka Kaneva , Jyotsna Batra , Amanda B Spurdle , Judith A Clements , Manuel R Teixeira , Ed Dicks , Andrew Lee , Alison M Dunning , Caroline Baynes , Don Conroy , Melanie J Maranian , Shahana Ahmed , Koveela Govindasami , Michelle Guy , Rosemary A Wilkinson , Emma J Sawyer , Angela Morgan , David P Dearnaley , Alan Horwich , Robert A Huddart , Vincent S Khoo , Christopher C Parker , Nicholas J Van As , Christopher J Woodhouse , Alan Thompson , Tim Dudderidge , Chris Ogden , Colin S Cooper , Artitaya Lophatananon , Angela Cox , Melissa C Southey , John L Hopper , Dallas R English , Markus Aly , Jan Adolfsson , Jiangfeng Xu , Siqun L Zheng , Meredith Yeager , Rudolf Kaaks , W Ryan Diver , Mia M Gaudet , Mariana C Stern , Roman Corral , Amit D Joshi , Ahva Shahabi , Tiina Wahlfors , Teuvo L J Tammela , Anssi Auvinen , Jarmo Virtamo , Peter Klarskov , Børge G Nordestgaard , M Andreas Røder , Sune F Nielsen , Stig E Bojesen , Afshan Siddiq , Liesel M Fitzgerald , Suzanne Kolb , Erika M Kwon , Danielle M Karyadi , William J Blot , Wei Zheng , Qiuyin Cai , Shannon K McDonnell , Antje E Rinckleb , Bettina Drake , Graham Colditz , Dominika Wokolorczyk , Robert A Stephenson , Craig Teerlink , Heiko Muller , Dietrich Rothenbacher , Thomas A Sellers , Hui-Yi Lin , Chavdar Slavov , Vanio Mitev , Felicity Lose , Srilakshmi Srinivasan , Sofia Maia , Paula Paulo , Ethan Lange , Kathleen A Cooney , Antonis C Antoniou , Daniel Vincent , François Bacot , Daniel C Tessier , COGSâCancer Research UK GWASâELLIPSE (part of GAME-ON) Initiative , Australian Prostate Cancer Bioresource , UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology , UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators , PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium , Zsofia Kote-Jarai , Douglas F Easton |
2013-04-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21546767 |
Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes. Am. J. Nephrol. Mariana Murea , Lingyi Lu , Lijun Ma , Pamela J Hicks , Jasmin Divers , Caitrin W McDonough , Carl D Langefeld , Donald W Bowden , Barry I Freedman |
2011-01-01 |
IRX5,
ADAMTS5,
KLHL29,
SLC24A4,
DGUOK,
TET3,
EPHA7,
ESRRG,
PDZRN3,
SH3BP4,
ABCA4,
STEAP1B,
SVIP,
GAS2,
GCNT1,
COX18,
HAS2,
NRG1,
LOC339568,
IL6,
LOC400800,
PCSK2,
CPSF2,
GPATCH2,
PTPRM,
DHX35,
RPSAP9,
IRX3,
RIN3,
CALM2,
ADAMTS3,
RAPGEF5
|
| 22082156 |
A whole genome screen for HIV restriction factors. Retrovirology Li Liu , Nidia M M Oliveira , Kelly M Cheney , Corinna Pade , Hanna Dreja , Ann-Marie H Bergin , Viola Borgdorff , David H Beach , Cleo L Bishop , Matthias T Dittmar , Aine McKnight |
2011-01-01 |
SLC35B1,
RAPGEF3,
CTSC,
MRPL54,
AP2M1,
TMEM266,
NR2C2AP,
SHE,
COL4A3,
R3HDML,
LELP1,
ALDH1L2,
DAG1,
DNM2,
DSP,
E2F1,
ELF3,
ESRRA,
EVI2B,
ALCAM,
MARCH8,
FAM83B,
EFR3A,
RTF1,
RPRD2,
FAM208A,
FUCA2,
FUT1,
ALX3,
RNF19A,
GANC,
GAP43,
ZNF658,
OPTC,
PELP1,
GNG3,
INO80E,
COX18,
GSTZ1,
RAB37,
ICAM4,
KLK3,
JUNB,
KCNG1,
KCNN1,
ZNF761,
FADS3,
PATE2,
MPI,
LRRC24,
NIT1,
OSM,
CCDC53,
COX16,
THEM6,
POP5,
CHMP5,
NCKIPSD,
POLB,
PAF1,
TXNL4B,
WSB2,
NDUFA12,
KLHL7,
PCDHB8,
IL36G,
INPP5E,
TRIM27,
HAPLN2,
SCD,
MRPL17,
ALDH8A1,
SEBOX,
PLA2G2F,
SLC26A10,
SYT4,
ACTC1,
UQCRH,
ZNF124,
MKRN3,
TRIM25,
LRRC2,
SPAG16,
NPEPL1,
RMI1,
ZNF556,
ZNF430,
ZNF93,
INO80B,
HIST1H2BC,
C18orf21,
NLRC5,
MEX3B,
HSDL2,
FKBP6,
TMEM209,
DGKD,
B4GALT3,
GCNT3
|
| 20819778 |
Carcinogenesis Xiaofan Zhang , Hushan Yang , J Jack Lee , Edward Kim , Scott M Lippman , Fadlo R Khuri , Margaret R Spitz , Reuben Lotan , Waun K Hong , Xifeng Wu |
2010-12-01 |
BCL2L11,
CDK4,
CDKN1B,
CDKN2A,
CDKN2C,
EMC8,
PGRMC2,
ATP5L,
IGF2BP1,
DDX20,
ATG4A,
ADH5,
ADH6,
E2F7,
DDB2,
UGT3A2,
NQO1,
DNMT3B,
E2F2,
EPHX2,
ERN1,
EZH1,
FANCD2,
FEN1,
FGF2,
FGF5,
FGF9,
FOXO1,
DICER1,
SIRT3,
NEIL2,
RICTOR,
TXN2,
SULT4A1,
HSPB8,
AGO1,
GHRHR,
GHITM,
SMC1B,
TNFRSF21,
ENDOV,
GPER1,
COX18,
GPX7,
DROSHA,
GSTM3,
GSTM5,
XIAP,
BIRC5,
ICAM1,
IGFBP2,
IGFBP5,
FAS,
IL1R1,
KRAS,
ARNTL,
SMAD1,
SMAD3,
SMAD7,
MBD1,
MDM4,
KMT2A,
MTHFR,
MTR,
NDUFA6,
NFKBIB,
NODAL,
NOTCH1,
OGG1,
ATP5A1,
RRM2B,
GEMIN4,
IGF2-AS,
ANGPT4,
SUFU,
ATP6V1C1,
PLK1,
PMS2P3,
POLH,
PON1,
DGCR8,
PDGFC,
BAG1,
BIRC6,
XPO5,
BAX,
ALDH18A1,
RAD51D,
RAN,
RET,
BCL2L2,
RING1,
RPA1,
RPS6KA3,
RPS6KB1,
RPS6KB2,
RRM1,
RXRA,
SMO
|
| 20877624 |
Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. PLoS One Sher L Hendrickson , James A Lautenberger , Leslie Wei Chinn , Michael Malasky , Efe Sezgin , Lawrence A Kingsley , James J Goedert , Gregory D Kirk , Edward D Gomperts , Susan P Buchbinder , Jennifer L Troyer , Stephen J O'Brien |
2010-09-21 | - |
| 20200953 |
Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study. J. Bone Miner. Res. David Karasik , Yi-Hsiang Hsu , Yanhua Zhou , L Adrienne Cupples , Douglas P Kiel , Serkalem Demissie |
2010-07-01 |
RAPGEF4,
CADM4,
FAM13C,
SLC35F1,
ANKRD17,
COX18,
CD300E,
IRAK2,
LMO1,
NELL1,
TMEM70,
PTPRD,
TTC23,
SCG2,
CAMKMT,
ITIH5,
CBLN1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
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目前还没有研究热点人员