| Type | Description |
|---|---|
| Definition | F-box and WD repeat domain containing 12 |
| Date | Results | Publications |
|---|---|---|
| 2016-10-08 12:20:00 | FBXW12 gene is deleted in approximately ten percent of the epithelial ovarian cancer cases studied; such deletions comprised either the FBXW12 promoter or the mRNA-encoding region. | 26617728 |
| 2016-03-26 12:06:00 | FBXW12 functions as an E3 ligase constituent to ubiquitinate and degrade IL-22R and that therapeutic FBXW12 inhibition may enhance IL-22 signaling and bolster mucosal host defense and infection containment. | 26171402 |
| 2010-01-21 00:00:00 | FBXO35 gene had a ubiquitously low expression pattern in most human adult tissues. FBXO35 gene was found located in chromosome 3p21. | 15040455 |
| Type | IDs |
|---|---|
| Synonymous | FBW12, FBXO12, FBXO35 |
| Gene |
UniProtKB-ID:
FBW12_HUMAN
UniprotKB:
Q6X9E4
UniParc:
UPI000198CAE2,
UPI00004123F1,
UPI00005764F0
EMBL:
AY247969,
AC104448,
BC101304,
BC101305
Ensembl:
ENSG00000164049
KO:
hsa:285231
|
| Nucleutide sequences |
EMBL-CDS:
AAI01306.1,
AAP75562.1,
AAI01305.1
Ensembl_TRS:
ENST00000296438,
ENST00000445170,
ENST00000415155
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000414683,
ENSP00000406139,
ENSP00000296438
RefSeq:
NP_996985.2,
XP_016861713.1,
NP_001153401.1,
NP_001153399.1
|
| Others |
UniRef100:
UniRef100_Q6X9E4
UniRef90:
UniRef90_Q6X9E4
UniRef50:
UniRef50_Q6X9E4
UniGene:
Hs.288793
CCDS:
CCDS54577.1,
CCDS2764.1,
CCDS54578.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29987050 |
Proc. Natl. Acad. Sci. U.S.A. Tengfei Xiao , Wei Li , Xiaoqing Wang , Han Xu , Jixin Yang , Qiu Wu , Ying Huang , Joseph Geradts , Peng Jiang , Teng Fei , David Chi , Chongzhi Zang , Qi Liao , Jonathan Rennhack , Eran Andrechek , Nanlin Li , Simone Detre , Mitchell Dowsett , Rinath M Jeselsohn , X Shirley Liu , Myles Brown |
2018-07-31 | - |
| 27432908 |
Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family. Mol Cell Proteomics Xu Li , Kim My Tran , Kathryn E Aziz , Alexey V Sorokin , Junjie Chen , Wenqi Wang |
2016-09-01 | - |
| 26171402 |
J Immunol Res Joseph Franz , Jacob Jerome , Travis Lear , Qiaoke Gong , Nathaniel M Weathington |
2015-01-01 |
FBXW12,
IL22RA1,
SKP1
|
| 26617728 |
Int J Clin Exp Pathol Elsa De La Chesnaye , Juan Pablo Méndez , Ricardo López-Romero , MarÃa De Los Angeles Romero-Tlalolini , MarÃa Dolores Vergara , Mauricio Salcedo , Sergio R Ojeda |
2015-01-01 | - |
| 19028597 |
Int J Biochem Cell Biol Frédéric Ebstein , Nicole Lange , Sabrina Urban , Ulrike Seifert , Elke Krüger , Peter-Michael Kloetzel |
2009-05-01 | - |
| 15520277 |
Systematic analysis and nomenclature of mammalian F-box proteins. Genes Dev. Jianping Jin , Timothy Cardozo , Ruth C Lovering , Stephen J Elledge , Michele Pagano , J Wade Harper |
2004-11-01 |
Fbxl14,
Fbxw11,
Fbxo4,
Fbxo38,
Fbxw17,
Fbxo40,
Fbxw13,
Fbxl21,
Fbxo42,
Fbxw10,
Fbxl16,
Fbxo11,
Kdm2a,
Fbxo44,
Fbxo21,
Fbxw8,
Fbxl18,
Fbxo27,
Fbxl19,
Fbxw19,
Fbxl5,
Fbxo46,
Fbxo45,
Fbxl4,
Fbxo10,
Skp2,
Fbxw2,
Fbxw4,
Fbxw5,
Fbxl6,
Kdm2b,
Fbxl12,
Fbxw16,
Fbxl13,
Fbxo41,
Lmo7,
Fbxw15,
Fbxw20,
Fbxl7,
Fbxw7,
Fbxw14,
Fbxl17,
Fbxo16,
Fbxo17,
Fbxo15,
Fbxl8,
Fbxl3,
Fbxw18,
Fbxo3,
Fbxo39,
Fbxo36,
Fbxo25,
Fbxo32,
Fbxo28,
Fbxl15,
Fbxw9,
Fbxo24,
Fbxo30,
Fbxo22,
Fbxl2,
Fbxl20,
Fbxl22,
Fbxo43,
Fbxo34,
Fbxo17,
Myc,
Fbxl4,
jet,
Fbw5,
Rca1,
CycE,
CG9003,
CG6758,
Ppa,
ago,
CG4911,
pall,
CG32085,
CG11658,
Skp2,
Kdm2,
FBXO11,
CG5961,
Fbxl7,
slmb,
CG2010,
FBXW10,
FBXO27,
FBXO36,
FBXL14,
FBXL16,
FBXO41,
FBXO39,
FBXO45,
FBXO15,
FBXL13,
FBXO28,
FBXO46,
FBXO33
|
| 15040455 |
cDNA cloning and expression analysis of a novel human F-box domain containing gene. Mol. Biol. Rep. Li Zeng , Shaohua Gu , Yao Li , Wenhu Wang , Yan Huang , Xin Ye , Jian Xu , Enpeng Zhao , Chaoneng Ji , Kang Ying , Yi Xie , Yumin Mao |
2004-03-01 | - |
| 14702039 |
Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. Toshio Ota , Yutaka Suzuki , Tetsuo Nishikawa , Tetsuji Otsuki , Tomoyasu Sugiyama , Ryotaro Irie , Ai Wakamatsu , Koji Hayashi , Hiroyuki Sato , Keiichi Nagai , Kouichi Kimura , Hiroshi Makita , Mitsuo Sekine , Masaya Obayashi , Tatsunari Nishi , Toshikazu Shibahara , Toshihiro Tanaka , Shizuko Ishii , Jun-ichi Yamamoto , Kaoru Saito , Yuri Kawai , Yuko Isono , Yoshitaka Nakamura , Kenji Nagahari , Katsuhiko Murakami , Tomohiro Yasuda , Takao Iwayanagi , Masako Wagatsuma , Akiko Shiratori , Hiroaki Sudo , Takehiko Hosoiri , Yoshiko Kaku , Hiroyo Kodaira , Hiroshi Kondo , Masanori Sugawara , Makiko Takahashi , Katsuhiro Kanda , Takahide Yokoi , Takako Furuya , Emiko Kikkawa , Yuhi Omura , Kumi Abe , Kumiko Kamihara , Naoko Katsuta , Kazuomi Sato , Machiko Tanikawa , Makoto Yamazaki , Ken Ninomiya , Tadashi Ishibashi , Hiromichi Yamashita , Katsuji Murakawa , Kiyoshi Fujimori , Hiroyuki Tanai , Manabu Kimata , Motoji Watanabe , Susumu Hiraoka , Yoshiyuki Chiba , Shinichi Ishida , Yukio Ono , Sumiyo Takiguchi , Susumu Watanabe , Makoto Yosida , Tomoko Hotuta , Junko Kusano , Keiichi Kanehori , Asako Takahashi-Fujii , Hiroto Hara , Tomo-o Tanase , Yoshiko Nomura , Sakae Togiya , Fukuyo Komai , Reiko Hara , Kazuha Takeuchi , Miho Arita , Nobuyuki Imose , Kaoru Musashino , Hisatsugu Yuuki , Atsushi Oshima , Naokazu Sasaki , Satoshi Aotsuka , Yoko Yoshikawa , Hiroshi Matsunawa , Tatsuo Ichihara , Namiko Shiohata , Sanae Sano , Shogo Moriya , Hiroko Momiyama , Noriko Satoh , Sachiko Takami , Yuko Terashima , Osamu Suzuki , Satoshi Nakagawa , Akihiro Senoh , Hiroshi Mizoguchi , Yoshihiro Goto , Fumio Shimizu , Hirokazu Wakebe , Haretsugu Hishigaki , Takeshi Watanabe , Akio Sugiyama , Makoto Takemoto , Bunsei Kawakami , Masaaki Yamazaki , Koji Watanabe , Ayako Kumagai , Shoko Itakura , Yasuhito Fukuzumi , Yoshifumi Fujimori , Megumi Komiyama , Hiroyuki Tashiro , Akira Tanigami , Tsutomu Fujiwara , Toshihide Ono , Katsue Yamada , Yuka Fujii , Kouichi Ozaki , Maasa Hirao , Yoshihiro Ohmori , Ayako Kawabata , Takeshi Hikiji , Naoko Kobatake , Hiromi Inagaki , Yasuko Ikema , Sachiko Okamoto , Rie Okitani , Takuma Kawakami , Saori Noguchi , Tomoko Itoh , Keiko Shigeta , Tadashi Senba , Kyoka Matsumura , Yoshie Nakajima , Takae Mizuno , Misato Morinaga , Masahide Sasaki , Takushi Togashi , Masaaki Oyama , Hiroko Hata , Manabu Watanabe , Takami Komatsu , Junko Mizushima-Sugano , Tadashi Satoh , Yuko Shirai , Yukiko Takahashi , Kiyomi Nakagawa , Koji Okumura , Takahiro Nagase , Nobuo Nomura , Hisashi Kikuchi , Yasuhiko Masuho , Riu Yamashita , Kenta Nakai , Tetsushi Yada , Yusuke Nakamura , Osamu Ohara , Takao Isogai , Sumio Sugano |
2004-01-01 |
Slc9a8,
Nefm,
Hfe2,
AKT3,
ZBTB11-AS1,
LOC100034248,
PDZK1P1,
DDTL,
LOC100049716,
ACOT8,
GNPDA1,
ZBTB33,
GTF2IP4,
POM121C,
ZSCAN30,
SRA1,
SNORD123,
UCKL1-AS1,
ZGLP1,
LOC100125918,
LINC00322,
LOC100127940,
HECW1-IT1,
LOC100127955,
LOC100127972,
LOC100127974,
FAM229A,
LOC100128076,
STAU2-AS1,
LOC100128164,
TMPO-AS1,
LOC100128219,
LOC100128239,
LOC100128253,
TNK2-AS1,
DNM1P35,
LOC100128288,
DLG5-AS1,
LOC100128310,
TRAPPC3L,
FAM83H-AS1,
LOC100128361,
LOC100128364,
FAM225B,
LOC100128386,
LOC100128398,
ASTN2-AS1,
C1orf132,
MYHAS,
LOC100128651,
LINC00476,
SRRM2-AS1,
GPR158-AS1,
LINC01165,
VPS9D1-AS1,
FAM66B,
GATA6-AS1,
LINC01310,
LOC100128979,
LOC100128988,
LOC100129034,
SEMA3F-AS1,
UNQ6494,
LOC100129115,
KHDC1L,
LOC100129175,
MATN1-AS1,
SLC39A12-AS1,
LOC100129297,
LOC100129312,
LINC00484,
LOC100129397,
LOC100129406,
DDC-AS1,
LOC100129434,
LOC100129447,
LOC100129455,
LYRM4-AS1,
ZNF37BP,
LOC100129516,
LOC100129518,
LOC100129540,
LOC100129572,
FAM47E,
LOC100129620,
LOC100129648,
C9orf173-AS1,
LOC100129775,
SLC25A21-AS1,
PCOLCE-AS1,
SCOC-AS1,
LOC100129884,
LOC100129894,
LOC100129917,
LOC100129935,
LOC100130078,
LOC100130111,
MAPT-IT1,
MIR124-2HG
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员