| Type | Description |
|---|---|
| Definition | transcription elongation factor GreB |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:35:00 | Nascent RNA sequencing identifies a widespread sigma70-dependent pausing regulated by Gre factors in bacteria. | 33568644 |
| 2020-05-30 12:58:00 | Data suggest that rRNA promoters are inhibited by the secondary channel factors (SCFs) transcription factors GreB and DksA because their short-lived RNA polymerases (RNAPs) complexes do not allow sufficient time for SCFs to dissociate. | 30720429 |
| 2020-01-25 13:09:00 | These reconstructions provide insight into the catalytic mechanism and dynamics of RNA cleavage and extension and suggest how GreB targets backtracked complexes without interfering with canonical transcription | 31103420 |
| 2018-04-21 10:54:00 | GreB binds to actively elongating complexes at nearly diffusion-limited rates but remains bound for only 0.3-0.5 s. Bound GreB inhibits transcript elongation only partially. GreB binds rapidly and randomly to elongation complexes, patrolling for those requiring nucleolytic rescue, and its short residence time minimizes RNAP inhibition | 28137878 |
| 2017-07-15 10:34:00 | overexpression of GreB in DeltagreA cells reduced the misincorporation errors to wild-type levels, demonstrating that GreB at high concentration could substitute for GreA in RNA proofreading activity in vivo. | 28341651 |
| Type | IDs |
|---|---|
| Synonymous | ECK3393 |
| Gene |
UniProtKB-ID:
GREB_ECOLI
UniprotKB:
P30128
UniParc:
UPI000012BABF
EMBL:
U81522,
U00096,
AP009048,
U18997
EnsemblGenome:
b3406,
BAE77885
KO:
ecj:JW3369,
eco:b3406
|
| Nucleutide sequences |
EMBL-CDS:
BAE77885.1,
AAA58203.1,
AAB39763.1,
AAC76431.2
EnsemblGenome_TRS:
AAC76431,
BAE77885
|
| Protein sequencees |
EnsemblGenome_PRO:
BAE77885,
AAC76431
RefSeq:
YP_026216.2
|
| Others |
UniRef100:
UniRef100_P30128
UniRef90:
UniRef90_P30128
UniRef50:
UniRef50_P30128
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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