| Type | Description |
|---|---|
| Definition | cytochrome P450 family 4 subfamily A member 22 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 11:30:00 | Study demonstrate that the CYP4A22 gene codes for an active enzyme. It catalyzes the hydroxylation of both lauric and myristic acids. The structural model of CYP4A22 and substrate docking experiments suggest that its broadened spectrum of catalyzed reactions results from increased residual mobility of active site residue Phe320 and that arginines Arg96 and Arg233 are essential for substrate recognition. | 31199497 |
| 2011-12-03 10:51:00 | Data suggest that results could be helpful for further investigations of the potential role of CYP4A variants in the genetic susceptibility to cardiovascular diseases such as arterial hypertension. | 21820496 |
| 2010-05-31 11:07:00 | A homology model has been constructed for CYP4A22 and refined by molecular dynamics simulation. | 20079672 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CP4AM_HUMAN,
Q5TCH5_HUMAN,
A5PL05_HUMAN,
A5PKT5_HUMAN,
A0A087WZX9_HUMAN
UniprotKB:
Q5TCH4,
Q5TCH5,
A5PL05,
A5PKT5,
A0A087WZX9
UniParc:
UPI00015657DD,
UPI000387B318,
UPI000156576F,
UPI00002371F0,
UPI0000470B16,
UPI0001761631
EMBL:
BC148248,
AL135960,
BC142690,
AY280372,
AY280371,
AF208532,
BC142607
Ensembl:
ENSG00000162365
KO:
hsa:284541
|
| Nucleutide sequences |
EMBL-CDS:
AAQ21367.1,
CAI19737.1,
AAF76722.1,
AAQ21368.1,
CAI19738.1,
AAI48249.1,
CAI19736.1,
AAI42691.1,
AAI42608.1
Gene_ORFName:
RP1-18D14.1-003
Ensembl_TRS:
ENST00000371891,
ENST00000371890,
ENST00000619754
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000360958,
ENSP00000360957,
ENSP00000482952
RefSeq:
XP_005270824.1,
NP_001010969.2,
XP_005270827.1,
NP_001295031.1
|
| Others |
UniRef100:
UniRef100_Q5TCH5,
UniRef100_A5PL05,
UniRef100_Q5TCH4,
UniRef100_A5PKT5
UniRef90:
UniRef90_V9GZ77,
UniRef90_Q5TCH4
UniRef50:
UniRef50_P08516,
UniRef50_A2A8S9
UniGene:
Hs.726474
CCDS:
CCDS30707.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员