| Type | Description |
|---|---|
| Definition | V-set and transmembrane domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:20:00 | Signal Inhibitory Receptor on Leukocytes-1 is highly expressed on lung monocytes, but absent on mononuclear phagocytes in skin and colon. | 32942189 |
| 2020-08-13 18:51:00 | Signal inhibitory receptor on leukocytes (SIRL)-1 and leukocyte- associated immunoglobulin-like receptor (LAIR)-1 regulate neutrophil function in infants. | 31843567 |
| 2017-08-12 10:45:00 | VSTM1 rs612529T is associated with a complete demethylation of the VSTM1 promoter and allele-specific upregulation of SIRL-1 expression in monocytes. | 28219444 |
| 2017-07-29 11:40:00 | findings show that SIRL-1 attenuates neutrophil extracellular traps (NET) release by neutrophils in response to distinct triggers, including opsonized Staphylococcus aureus and inflammatory danger signals; define SIRL-1 as an intervention point of benefit to suppress neutrophil extracellular trap formation in disease while preserving intracellular antimicrobial defense | 27016607 |
| 2016-07-16 10:47:00 | VSTM1-v2 might be a biomarker of rheumatoid arthritis (RA) and a novel factor in the pathogenesis of RA. | 26760041 |
| Type | IDs |
|---|---|
| Synonymous | SIRL-1, SIRL1, UNQ3033 |
| Gene |
UniProtKB-ID:
VSTM1_HUMAN,
D2DJS5_HUMAN,
D2DJS6_HUMAN
UniprotKB:
Q6UX27,
D2DJS5,
D2DJS6
UniParc:
UPI0001C08D4A,
UPI0000202B78,
UPI00001D8195,
UPI0001C08D49,
UPI000058E04A
EMBL:
FJ584318,
AC012314,
BC100943,
DQ479397,
FJ584320,
BC100942,
FN398145,
FJ584319,
AY358542,
FJ584317,
FJ584316
Ensembl:
ENSG00000277607,
ENSG00000189068,
ENSG00000276066,
ENSG00000275577,
ENSG00000274953,
ENSG00000276363,
ENSG00000274887,
ENSG00000276159,
ENSG00000275962,
ENSG00000275330
KO:
hsa:284415
|
| Nucleutide sequences |
EMBL-CDS:
ACU00109.1,
ABF19807.1,
ACU00108.1,
ACU00110.1,
CAZ61324.1,
AAQ88906.1,
AAI00943.1,
AAI00944.1,
ACU00111.1,
ACU00112.1
Gene_ORFName:
UNQ3033/PRO9835
Ensembl_TRS:
ENST00000447872,
ENST00000617115,
ENST00000612436,
ENST00000612105,
ENST00000338372,
ENST00000619921,
ENST00000613042,
ENST00000617776,
ENST00000612864,
ENST00000610629,
ENST00000622762,
ENST00000610794,
ENST00000615508,
ENST00000620474,
ENST00000617862,
ENST00000615235,
ENST00000610804,
ENST00000376626,
ENST00000619024,
ENST00000616717,
ENST00000617281,
ENST00000611293,
ENST00000613085,
ENST00000620314,
ENST00000617097,
ENST00000614572,
ENST00000616582,
ENST00000366170,
ENST00000612639,
ENST00000614154,
ENST00000615538,
ENST00000612942
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000483411,
ENSP00000482555,
ENSP00000401926,
ENSP00000484844,
ENSP00000481140,
ENSP00000480547,
ENSP00000483797,
ENSP00000483412,
ENSP00000484806,
ENSP00000481977,
ENSP00000484699,
ENSP00000343366,
ENSP00000365813,
ENSP00000480383,
ENSP00000478582,
ENSP00000484886,
ENSP00000482985,
ENSP00000479748,
ENSP00000482197,
ENSP00000483104,
ENSP00000480533,
ENSP00000479198,
ENSP00000479956,
ENSP00000484758,
ENSP00000478214,
ENSP00000480671,
ENSP00000482300,
ENSP00000479856,
ENSP00000483560,
ENSP00000479529,
ENSP00000483406,
ENSP00000444153
RefSeq:
XP_011525151.1,
XP_011525150.1,
NP_001275722.1,
NP_001275721.1,
XP_011525148.1,
NP_001275720.1,
XP_016882155.1,
NP_940883.2,
XP_011525149.1,
XP_011525147.1
|
| Others |
UniRef100:
UniRef100_Q6UX27,
UniRef100_D2DJS6,
UniRef100_D2DJS5
UniRef90:
UniRef90_D2DJS5,
UniRef90_Q6UX27,
UniRef90_A0A0G2JPS7
UniRef50:
UniRef50_A0A0G2JPS7,
UniRef50_Q6UX27,
UniRef50_D2DJS5
UniGene:
Hs.444431
CCDS:
CCDS74442.1,
CCDS12872.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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