| Type | Description |
|---|---|
| Definition | laminin subunit alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:28:00 | Organisation of extracellular matrix proteins laminin and agrin in pericapillary basal laminae in mouse brain. | 32072250 |
| 2020-01-04 10:49:00 | intrinsic interaction between AG73 in the tumor environment and the proteoglycan receptors Sdcs on breast cancer cells in supporting tumor cell adhesion and invasion through filopodia, is an important step in cancer metastasis. | 31183318 |
| 2017-12-02 12:12:00 | We report here a severe defect of neuromuscular transmission in a consanguineous patient with a homozygous variant in the laminin alpha-5 subunit gene (LAMA5). The variant c.8046C>T (p.Arg2659Trp) is rare and has a predicted deleterious effect. The affected individual, who also carries a rare homozygous sequence variant in LAMA1, had muscle weakness, myopia, and facial tics | 28544784 |
| 2017-10-21 11:46:00 | LAMA1 SNP rs2089760 plays an important role in the development of PM. | 26862816 |
| 2017-08-26 11:50:00 | LAMA1 deficiency can lead to alteration in cytoskeletal dynamics, which may invariably lead to alteration in dendrite growth and axonal formation. Patient-derived fibroblasts have impaired adhesion, reduced migration, abnormal morphology and increased apoptosis due to impaired activation of Cdc42, a member of the Rho family of GTPases that is involved in cytoskeletal dynamics. | 27095636 |
| Type | IDs |
|---|---|
| Synonymous | LAMA, PTBHS, S-LAM-alpha |
| Gene |
UniProtKB-ID:
LAMA1_HUMAN
UniprotKB:
P25391
UniParc:
UPI00001C1FF9
EMBL:
X58531,
AP005062,
AP002409,
AP005210
Ensembl:
ENSG00000101680
KO:
hsa:284217
|
| Nucleutide sequences |
EMBL-CDS:
CAA41418.1
Ensembl_TRS:
ENST00000389658
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000374309
RefSeq:
NP_005550.2
|
| Others |
UniRef100:
UniRef100_P25391
UniRef90:
UniRef90_P25391
UniRef50:
UniRef50_P19137
UniGene:
Hs.270364
CCDS:
CCDS32787.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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