| Type | Description |
|---|---|
| Definition | caveolae associated protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:31:00 | PTRF/CAVIN1, regulated by SHC1 through the EGFR pathway, is found in urine exosomes as a potential biomarker of ccRCC. | 31605605 |
| 2020-08-01 13:00:00 | The p.Glu176Argfs mutation imparts high positive charge to the cavin-1 LZD2 domain. The mutation imparts high membrane-binding propensity to this region. The peptide stretch displays preferential binding to the negatively-charged liposomes. Binding to the cholesterol/sphingomyelin-rich domain is also enhanced. | 31706570 |
| 2019-12-28 12:27:00 | Overexpression of PTRF led to MAPK inhibitors (MAPKi) resistance in melanoma, increased cell adhesion and sphere formation. In addition, immunohistochemistry of patient samples showed that PTRF expression levels were a significant biomarker of poor progression-free survival. | 31267558 |
| 2019-12-21 10:34:00 | Data evaluate the interaction between one candidate interactor protein, protein phosphatase 1 alpha (PP1alpha), and Cavin-1 and -3 and show that UV treatment causes release of Cavin3 from caveolae allowing interaction with, and inhibition of, PP1alpha. | 31332168 |
| 2019-12-14 11:41:00 | High CAVIN1 expression is associated with glioblastoma. | 30949900 |
| Type | IDs |
|---|---|
| Synonymous | CAVIN, CGL4, FKSG13, PTRF, cavin-1 |
| Gene |
UniProtKB-ID:
CAVN1_HUMAN
UniprotKB:
Q6NZI2
UniParc:
UPI00003B5C79,
UPI00001AF3C2,
UPI00000737F6
EMBL:
BC008849,
CH471152,
AK314389,
BC066123,
BC073759,
BC004295,
AF000421,
AF312393
Ensembl:
ENSG00000177469
KO:
hsa:284119
|
| Nucleutide sequences |
EMBL-CDS:
AAH66123.1,
AAG27093.1,
BAG37014.1,
AAH73759.1,
AAH04295.1,
EAW60828.1,
AAC63404.1,
AAH08849.1
Gene_ORFName:
FKSG13
Ensembl_TRS:
ENST00000357037
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000349541
RefSeq:
XP_005257299.1,
NP_036364.2
|
| Others |
UniRef100:
UniRef100_Q6NZI2
UniRef90:
UniRef90_Q6NZI2
UniRef50:
UniRef50_Q6NZI2
UniGene:
Hs.437191
CCDS:
CCDS11425.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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