| Type | Description |
|---|---|
| Definition | transmembrane protein 102 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-02 12:21:00 | our findings reveal a novel oncogenic contribution of CBAP in T-ALL leukemic cells, in addition to its original pro-apoptotic function in cytokine-dependent cell lines and primary hematopoietic cells, by demonstrating its functional role in the regulation of Akt-TSC2-mTORC1 signaling for leukemia cell proliferation. Thus, CBAP represents a novel therapeutic target for many types of cancers and metabolic diseases | 30266989 |
| 2013-11-16 11:15:00 | CBAP indeed can function as a novel signaling component within the ZAP70/Vav1/talin complex and plays an important role in regulating chemokine-promoted T-cell trafficking. | 23620790 |
| 2010-01-21 00:00:00 | Modulates granulocyte-macrophage colony-stimulating factor-deprivation-induced apoptosis possibly via a novel mechanism involving interaction with an unliganded cytokine receptor common beta subunit molecule. | 17828305 |
| 2008-02-08 13:19:00 | CBAP (Common receptor Beta chain Associating Protein) is a putative transmembrane protein which associates preferentially with unliganded GM-CSFR beta chain. It functions as a pro-apoptotic protein and is widely expressed in various cell types. | 17828305 |
| Type | IDs |
|---|---|
| Synonymous | CBAP |
| Gene |
UniProtKB-ID:
TM102_HUMAN
UniprotKB:
Q8N9M5
UniParc:
UPI000000DB5A
EMBL:
AK094197,
CH471108,
BC046189
Ensembl:
ENSG00000181284,
ENSG00000284228
KO:
hsa:284114
|
| Nucleutide sequences |
EMBL-CDS:
BAC04306.1,
AAH46189.1,
EAW90190.1,
EAW90189.1
Ensembl_TRS:
ENST00000323206,
ENST00000396568,
ENST00000639387,
ENST00000638427
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379815,
ENSP00000491290,
ENSP00000491063,
ENSP00000315387
RefSeq:
NP_848613.1,
NP_001307373.1
|
| Others |
UniRef100:
UniRef100_Q8N9M5
UniRef90:
UniRef90_Q8N9M5
UniRef50:
UniRef50_Q8N9M5
UniGene:
Hs.655662
CCDS:
CCDS11104.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 30266989 |
Oncogene Yun-Jung Chiang , Wei-Ting Liao , Kun-Chin Ho , Shih-Hao Wang , Yu-Guang Chen , Ching-Liang Ho , Shiu-Feng Huang , Lee-Yung Shih , Hsin-Fang Yang-Yen , Jeffrey Jong-Young Yen |
2019-02-01 | - |
| 29507755 |
Cell Discov Yanan Yue , Jun Liu , Xiaolong Cui , Jie Cao , Guanzheng Luo , Zezhou Zhang , Tao Cheng , Minsong Gao , Xiao Shu , Honghui Ma , Fengqin Wang , Xinxia Wang , Bin Shen , Yizhen Wang , Xinhua Feng , Chuan He , Jianzhao Liu |
2018-01-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27173435 |
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Nat Commun Karsten Boldt , Jeroen van Reeuwijk , Qianhao Lu , Konstantinos Koutroumpas , Thanh-Minh T Nguyen , Yves Texier , Sylvia E C van Beersum , Nicola Horn , Jason R Willer , Dorus A Mans , Gerard Dougherty , Ideke J C Lamers , Karlien L M Coene , Heleen H Arts , Matthew J Betts , Tina Beyer , Emine Bolat , Christian Johannes Gloeckner , Khatera Haidari , Lisette Hetterschijt , Daniela Iaconis , Dagan Jenkins , Franziska Klose , Barbara Knapp , Brooke Latour , Stef J F Letteboer , Carlo L Marcelis , Dragana Mitic , Manuela Morleo , Machteld M Oud , Moniek Riemersma , Susan Rix , Paulien A Terhal , Grischa Toedt , Teunis J P van Dam , Erik de Vrieze , Yasmin Wissinger , Ka Man Wu , Gordana Apic , Philip L Beales , Oliver E Blacque , Toby J Gibson , Martijn A Huynen , Nicholas Katsanis , Hannie Kremer , Heymut Omran , Erwin van Wijk , Uwe Wolfrum , François Kepes , Erica E Davis , Brunella Franco , Rachel H Giles , Marius Ueffing , Robert B Russell , Ronald Roepman , UK10K Rare Diseases Group |
2016-05-13 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 23620790 |
PLoS ONE Yun-Jung Chiang , Kun-Chin Ho , Chien-Tsang Sun , Jeng-Jiann Chiu , Fang-Jen Lee , Fang Liao , Hsin-Fang Yang-Yen , Jeffrey Jong-Young Yen |
2013-01-01 |
Ccr6,
Cdc42,
Cxcr3,
Cxcr4,
Ccr5,
Ccr7,
Icam1,
Cxcl10,
Itgb1,
Itgb2,
Ccl21a,
Rac1,
Ccl20,
Ccl5,
Cxcl12,
Sell,
Vcam1,
Zap70,
Slc14a2,
Tmem102,
TMEM102,
ICAM1,
CXCL10,
ITGB1,
ITGB2,
RAC1,
CCL5,
CCL20,
CCL21,
CXCL12,
VCAM1,
ZAP70,
CXCR4,
SLC14A2,
CDC42
|
| 21273506 |
Proc. Natl. Acad. Sci. U.S.A. Christopher J Westlake , Lisa M Baye , Maxence V Nachury , Kevin J Wright , Karen E Ervin , Lilian Phu , Cecile Chalouni , John S Beck , Donald S Kirkpatrick , Diane C Slusarski , Val C Sheffield , Richard H Scheller , Peter K Jackson |
2011-02-15 |
rab11al,
rab11bb,
rab11a,
rab3ip,
RAB3IP,
TRAPPC10,
TRAPPC6A,
RAB11A
|
| 17828305 |
Oncogene C-J Kao , Y-J Chiang , P-H Chen , K-R Lin , P-I Hwang , H-F Yang-Yen , J J-Y Yen |
2008-02-28 |
Tmem102,
CSF2RB,
TMEM102
|
| 17353931 |
Large-scale mapping of human protein-protein interactions by mass spectrometry. Mol. Syst. Biol. Rob M Ewing , Peter Chu , Fred Elisma , Hongyan Li , Paul Taylor , Shane Climie , Linda McBroom-Cerajewski , Mark D Robinson , Liam O'Connor , Michael Li , Rod Taylor , Moyez Dharsee , Yuen Ho , Adrian Heilbut , Lynda Moore , Shudong Zhang , Olga Ornatsky , Yury V Bukhman , Martin Ethier , Yinglun Sheng , Julian Vasilescu , Mohamed Abu-Farha , Jean-Philippe Lambert , Henry S Duewel , Ian I Stewart , Bonnie Kuehl , Kelly Hogue , Karen Colwill , Katharine Gladwish , Brenda Muskat , Robert Kinach , Sally-Lin Adams , Michael F Moran , Gregg B Morin , Thodoros Topaloglou , Daniel Figeys |
2007-01-01 |
PDCD6IP,
CHAF1A,
PARP3,
RANBP9,
SMC4,
UBA2,
SAE1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
ARPC2,
RAD50,
RASGRP1,
LRPPRC,
PDIA6,
G3BP1,
TRIM28,
CDK2,
CDK4,
PSME3,
CDK6,
PSMD14,
HNRNPR,
SRRM1,
DENND4A,
SF3B4,
LOC400927-CSNK1E,
SAP18,
SMNDC1,
BCAS2,
EIF1B,
SF3A1,
CDKN2A,
BCKDK,
PAK4,
CDKN2C,
CDO1,
YAP1,
CD2BP2,
UBAC1,
MCRS1,
BAIAP2,
PFDN6,
EIF3M,
SYNCRIP,
STK25,
MYBBP1A,
HYOU1,
NOP56,
SSSCA1,
GLRX3,
ARPC1A,
SPTLC1,
SORBS1,
SMC2,
PRPF8,
AHSA1,
PAICS,
MYL12A,
ATP5L,
NPRL2,
IGF2BP1,
IGF2BP3,
IGF2BP2,
PMVK,
PNMA2,
USP39,
AP4B1,
POLQ,
CFL1,
NUDC,
PTGES3,
MAP3K2,
GIPC1,
SRSF10,
NEK6,
NCKAP1,
IQGAP2,
MTHFD2,
SDCCAG3,
CLPX,
RUVBL2,
PGRMC1,
RAB10,
MALT1,
RNPS1,
MORF4L1,
KDELR1,
SF3A3,
SERINC3,
STIP1,
ACOT2,
EBNA1BP2,
YWHAQ,
GCN1,
SF3B2
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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