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284110 GSDMA

284110

GSDMA

gasdermin A

protein-coding

Homo sapiens

基因描述

Type Description
Definition gasdermin A

研究结论

Date Results Publications
2019-01-26 12:33:00 GSDMA is upregulated in systemic sclerosis monocyte-derived macrophages but not in the skin; and is an expression quantitative trait locus in systemic sclerosis macrophages and lipopolysaccharide/interferon gamma (IFNgamma)-stimulated monocytes. A systemic sclerosis macrophage transcriptome signature is characterized by upregulation of glycolysis, hypoxia and mTOR signaling and a downregulation of IFNgamma response pat... 29348297
2017-09-09 12:48:00 modest changes (8-13%) in promoter methylation levels of ZPBP2 and GSDMA may cause substantial changes in RNA levels and allelic expression of ZPBP2 and ORMDL3 is mediated by DNA methylation 28241063
2017-08-19 12:57:00 GSDMA was identified as a susceptibility gene for systemic sclerosis. 28314753
2016-12-31 11:10:00 we investigated the association between GSDMA and GSDMB variants and the incidence of adult and childhood asthma among Jordanians.An association between the GSDMB T/C single nucleotide polymorphism (SNP) genotype and the incidence of childhood asthma was found 26886240
2016-12-17 10:58:00 The local genotype influences methylation levels at SLC22A5 and ZPBP2 promoters independently of the asthma status. Further studies are necessary to confirm the relationship between GSDMA-ZPBP2 and SLC22A5 methylation and asthma in females and males separately. 26671913

名称对应

Type IDs
Synonymous FKSG9, GSDM, GSDM1
Gene
UniProtKB-ID: GSDMA_HUMAN
UniprotKB: Q96QA5
UniParc: UPI0000140D2A
EMBL: AB093591, AC090844, AK096439, AF307953, BC109197
Ensembl: ENSG00000167914
KO: hsa:284110
Nucleutide sequences
EMBL-CDS: AAI09198.1, AAL14426.1, BAC04790.1, BAC75636.1
Gene_ORFName: FKSG9
Ensembl_TRS: ENST00000301659, ENST00000635792
Protein sequencees
Ensembl_PRO: ENSP00000301659, ENSP00000490739
RefSeq: XP_016879992.1, NP_835465.2, XP_006721895.1, XP_016879993.1, XP_016879991.1, XP_011522953.1
Others
UniRef100: UniRef100_Q96QA5
UniRef90: UniRef90_Q96QA5
UniRef50: UniRef50_Q5Y4Y6
UniGene: Hs.448873
CCDS: CCDS45669.1

全选

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研究热度

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